Proceedings of the 1st International Conference for Health Research – BRIN (ICHR 2022)

The Effectiveness of Covid-19 Vaccination in Indonesian Population: A Case-Control Study Protocol

Authors
Sri Idaiani1, *, Nurhayati Nurhayati1, Delima Delima1, Harimat Hendarwan1, Lucie Widowati1, Ingan U. Tarigan1, Nurfi Afriansyah1, Sundari Wirasmi1, Diah Yunitawati1, Setyo Adiningsih1, Hadjar Siswantoro2, Tince A. Jovina2, Yenni Risniati2, Rossa Avrina2, Armaji K. Syarif2, Nita Prihartini2, Narendro Arifia2, Yusi D. Nurcahyani2, Evi I. Natalia2, Made D. Susilawati2, Jarir A. Thobari3
1Research Organization for Health, National Research and Innovation Agency, Jakarta, Indonesia
2Health Policy Agency, Ministry of Health, Jakarta, Indonesia
3Faculty of Medicine Public Health and Nursing, Universitas Gajah Mada, Yogyakarta, Indonesia
*Corresponding author. Email: sri.idaiani@brin.go.id
Corresponding Author
Sri Idaiani
Available Online 1 March 2023.
DOI
10.2991/978-94-6463-112-8_71How to use a DOI?
Keywords
Indonesia; COVID-19 vaccine; effectiveness; symptomatic COVID-19
Abstract

It is essential to prove a vaccination program's effectiveness before initiating such a program to the entire population. Accordingly, the government of Indonesia has conducted research at the beginning of the COVID-19 vaccination program. The general objective of the current study was to assess the effectiveness of COVID-19 vaccine against symptomatic COVID-19 incidence and its severity. This is a protocol study of an unmatched case-control study design. The subjects are health workers and members of the community. The case group is symptomatic COVID-19 as confirmed by the RT PCR or Antigen rapid tests taken during the data collection time on 13 January 2021 for the health workers and in February 2021 for non-health workers. Meanwhile, the control group consisted of people who are at least 18 years old and had never been diagnosed with COVID-19. The ratio of cases and controls in the health workers group is 1:4, while the ratio for the community group is 1:1. Based on the previous effectiveness study, the city of Bandung required 4625 health workers and 3834 non-health workers. The data for the study were collected from July to October 2021 in seven provinces and 14 districts/cities. The case group data were obtained from hospital medical records, while the control group data were collected from the same hospital and community living in areas heavily affected by COVID-19. Trained enumerators filled out the patient questionnaires, while the control group filled out the questionnaires themselves. The degree of severity of COVID-19 was obtained from the doctor in charge of the patients (DPJP). This study used the Lime Survey application from the link http://bit.ly/effectiveness_vaksin_c19. Data analysis was carried out separately for the groups of health workers and community groups. We calculated the odds ratio (OR) adjusted by age, gender, and comorbid diseases; then the effectiveness of the vaccination was designated as 1-OR. Vaccine effectiveness will be calculated based on the type of vaccine as well. The Indonesian government will use the results as scientific evidence of the effectiveness of COVID-19 vaccination in Indonesia.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Download article (PDF)

Volume Title
Proceedings of the 1st International Conference for Health Research – BRIN (ICHR 2022)
Series
Advances in Health Sciences Research
Publication Date
1 March 2023
ISBN
978-94-6463-112-8
ISSN
2468-5739
DOI
10.2991/978-94-6463-112-8_71How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Sri Idaiani
AU  - Nurhayati Nurhayati
AU  - Delima Delima
AU  - Harimat Hendarwan
AU  - Lucie Widowati
AU  - Ingan U. Tarigan
AU  - Nurfi Afriansyah
AU  - Sundari Wirasmi
AU  - Diah Yunitawati
AU  - Setyo Adiningsih
AU  - Hadjar Siswantoro
AU  - Tince A. Jovina
AU  - Yenni Risniati
AU  - Rossa Avrina
AU  - Armaji K. Syarif
AU  - Nita Prihartini
AU  - Narendro Arifia
AU  - Yusi D. Nurcahyani
AU  - Evi I. Natalia
AU  - Made D. Susilawati
AU  - Jarir A. Thobari
PY  - 2023
DA  - 2023/03/01
TI  - The Effectiveness of Covid-19 Vaccination in Indonesian Population: A Case-Control Study Protocol
BT  - Proceedings of the 1st International Conference for Health Research – BRIN (ICHR 2022)
PB  - Atlantis Press
SP  - 785
EP  - 795
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-112-8_71
DO  - 10.2991/978-94-6463-112-8_71
ID  - Idaiani2023
ER  -