The Potential of Secondary Metabolites from Indonesian Weeds in Asthma Management
- DOI
- 10.2991/978-94-6463-202-6_3How to use a DOI?
- Keywords
- Weed plants; Herbal medicine; Computational test; Euphorbia Hirta L; Mimosa Pudica L
- Abstract
Managing asthma with clinical drugs commonly has some adverse events and drug tolerance. Asthma management with minimal drug side effects is suitable for reducing asthma prevalence. Herbal medicine could apply to mild asthma or as an adjunct to standard asthma management. This study compares the chemical bonds between the secondary metabolites in Euphorbia Hirta L. and Mimosa Pudica L. with the beta-2 blocker drugs. This research design used computational testing to evaluate secondary metabolites compounds. We tested the binding between secondary metabolite compounds and β2 receptors using the iGEMDOCK application. Beta-2 blocker drugs in this paper were fenoterol hydrobromide (HBr) and salbutamol. In addition, data analysis with quantitative descriptive used the findings of the computational test using the docking method. The results indicated that the secondary metabolite compounds in Euphorbia Hirta L. and Mimosa Pudica L. leaf extracts had similar binding energy to beta-2 blocker drugs. In conclusion, the weed plants of Euphorbia Hirta L. and Mimosa Pudica L. have the potential to be herbal medicine for individuals with asthma.
- Copyright
- © 2023 The Author(s)
- Open Access
- Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
Cite this article
TY - CONF AU - Lathifah Yuliana Hastuti AU - Dias Setyawan PY - 2023 DA - 2023/06/26 TI - The Potential of Secondary Metabolites from Indonesian Weeds in Asthma Management BT - Proceedings of the 2nd International Conference of Health Innovation and Technology (ICHIT 2022) PB - Atlantis Press SP - 12 EP - 17 SN - 2468-5739 UR - https://doi.org/10.2991/978-94-6463-202-6_3 DO - 10.2991/978-94-6463-202-6_3 ID - Hastuti2023 ER -