Proceedings of the 2nd International Conference of Health Innovation and Technology (ICHIT 2022)

The Potential of Secondary Metabolites from Indonesian Weeds in Asthma Management

Authors
Lathifah Yuliana Hastuti1, *, Dias Setyawan2
1Universitas Darussalam Gontor, Ponorogo, East Java, 63471, Indonesia
2Universitas Negeri Malang, Malang, East Java, 65145, Indonesia
*Corresponding author. Email: lathifahyuliana99@gmail.com
Corresponding Author
Lathifah Yuliana Hastuti
Available Online 26 June 2023.
DOI
10.2991/978-94-6463-202-6_3How to use a DOI?
Keywords
Weed plants; Herbal medicine; Computational test; Euphorbia Hirta L; Mimosa Pudica L
Abstract

Managing asthma with clinical drugs commonly has some adverse events and drug tolerance. Asthma management with minimal drug side effects is suitable for reducing asthma prevalence. Herbal medicine could apply to mild asthma or as an adjunct to standard asthma management. This study compares the chemical bonds between the secondary metabolites in Euphorbia Hirta L. and Mimosa Pudica L. with the beta-2 blocker drugs. This research design used computational testing to evaluate secondary metabolites compounds. We tested the binding between secondary metabolite compounds and β2 receptors using the iGEMDOCK application. Beta-2 blocker drugs in this paper were fenoterol hydrobromide (HBr) and salbutamol. In addition, data analysis with quantitative descriptive used the findings of the computational test using the docking method. The results indicated that the secondary metabolite compounds in Euphorbia Hirta L. and Mimosa Pudica L. leaf extracts had similar binding energy to beta-2 blocker drugs. In conclusion, the weed plants of Euphorbia Hirta L. and Mimosa Pudica L. have the potential to be herbal medicine for individuals with asthma.

Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 2nd International Conference of Health Innovation and Technology (ICHIT 2022)
Series
Advances in Health Sciences Research
Publication Date
26 June 2023
ISBN
978-94-6463-202-6
ISSN
2468-5739
DOI
10.2991/978-94-6463-202-6_3How to use a DOI?
Copyright
© 2023 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

TY  - CONF
AU  - Lathifah Yuliana Hastuti
AU  - Dias Setyawan
PY  - 2023
DA  - 2023/06/26
TI  - The Potential of Secondary Metabolites from Indonesian Weeds in Asthma Management
BT  - Proceedings of the 2nd International Conference of Health Innovation and Technology (ICHIT 2022)
PB  - Atlantis Press
SP  - 12
EP  - 17
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-202-6_3
DO  - 10.2991/978-94-6463-202-6_3
ID  - Hastuti2023
ER  -