Phytochemical Screening and Antibacterial Activity of Senduduk Leaves (Melastoma malabathricum L.)
- DOI
- 10.2991/ahsr.k.211105.031How to use a DOI?
- Keywords
- Melastoma malabathricum L; Phytochemical Screening; Antibacterial; Kirby-Bauer Disc Susceptibility Test
- Abstract
Melastoma malabathricum L. leaves is a traditional plant native to tropical Asia, subtropical, and Pacific islands. This study aimed to investigate the antibacterial activity of senduduk leaves (Melastoma malabathricum L.) against bacteria Streptococcus pyogenes,and Klebsiella pneumonia. Method of extraction done by maceration using ethanol 70% to get the extract. The antibacterial activity of the extracts was determined by using Kirby-Bauer Disc Susceptibility Test and with a concentration of 25%, 50% and, 75%. The inhibition zone was recorded from senduduk leaves (Melastoma malabathricum L.) extract to indicate the highest antimicrobial activity from this plant. Based on the results of this study, the extract leaves can inhibit the growth of Streptococcus pyogenes in concentration 75% (21.8 mm) and Klebsiella pneumonia in concentration 75% (16 mm). The phytochemical analysis detected the presence of alkaloids, flavonoids, saponins, tannins, and terpenoids. The findings may be helpful to future investigators in identifying alternative and new bioactive secondary metabolites like antibiotics to treat resistant human pathogens.
- Copyright
- © 2021 The Authors. Published by Atlantis Press International B.V.
- Open Access
- This is an open access article under the CC BY-NC license.
Cite this article
TY - CONF AU - Sri Hainil AU - Henny Rachdiati AU - Dwi Prawita PY - 2021 DA - 2021/11/17 TI - Phytochemical Screening and Antibacterial Activity of Senduduk Leaves (Melastoma malabathricum L.) BT - Proceedings of the 2nd International Conference on Contemporary Science and Clinical Pharmacy 2021 (ICCSCP 2021) PB - Atlantis Press SP - 211 EP - 213 SN - 2468-5739 UR - https://doi.org/10.2991/ahsr.k.211105.031 DO - 10.2991/ahsr.k.211105.031 ID - Hainil2021 ER -