Effect of Cortex Lycii Radicis Ethanol-Extract on the Hypoglycemic and Hypolipidemic In Type 2 Diabetic Rats
- DOI
- 10.2991/icaset-16.2016.60How to use a DOI?
- Keywords
- Cortex lycii radicis ethanol-extract, Type 2 diabetic mellitus(T2DM), Hypoglycemic, Hypolipidemic
- Abstract
To observe effect of cortex lycii radicis ethanol-extract on the hypoglycemic and hypolipidemic in T2DM rats. T2DM rat modelinduced by intravenous injection small dose of streptozotocin (STZ) and feeding high fat-high glucose diet .The rats were randomly divided into blank control group, model control group, cortex lycii radicis ethanol-extract groups of high dose, medium dose and low dose, positive drug rosiglitazone group. Seven weeks after medication, to observe influence of cortex lycii radicis ethanol-extract on rat weight and the content in fasting blood glucose (FBG), serum insulin(INS), total cholesterol(TC), triglycerides(TG) and low density lipoprotein cholesterol (LDL-C). Compared blank control group with the other groups, there were no significant differences in various indicators of be detected(P>0.05). Compared with the model group, cortex lycii radicis ethanol-extract can reduced body weight, FBG, INS, TC, TG and LDL-C, increased INS of T2DM rats, the differences were significant (P<0.01or 0.05).Cortex lycii radicis ethanol-extract can lowers blood glucose and regulate blood lipid metabolism to some extent.
- Copyright
- © 2016, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Changlei Li AU - Xiji Shu AU - Xiaoqing Chen AU - Yuwei Liu AU - Huiling Yi AU - Wei Liu AU - Baomiao Ma PY - 2016/05 DA - 2016/05 TI - Effect of Cortex Lycii Radicis Ethanol-Extract on the Hypoglycemic and Hypolipidemic In Type 2 Diabetic Rats BT - Proceedings of the 2016 6th International Conference on Applied Science, Engineering and Technology PB - Atlantis Press SP - 303 EP - 307 SN - 2352-5401 UR - https://doi.org/10.2991/icaset-16.2016.60 DO - 10.2991/icaset-16.2016.60 ID - Li2016/05 ER -