Effects of Smoking on Rat Peptic Ulcer

DOI

10.2991/icaees-15.2015.118How to use a DOI?

Keywords

Smoking; Acetic acid; Gastric ulcer

Abstract

40 SD rats weighing 200 ± 10g were used, 12 of 40 rats were randomly selected as those in sham group, and the remaining 28 were used to establish the acetic acid-induced gastric ulcers to observe effects of smoking on the rat gastric ulcer and ulcer area. The acetic acid-induced gastric ulcer model in rats is reliable. Smoking can delay or the healing of ulcer, which may be related to the increase of gastric acid secretion induced by smoking, the increase in oxygen free radicals that can damage the mucosa of stomach, the decrease of pyloric sphincter tension, the reflux of bile and duodenal fluid to the stomach, and the reduction of prostaglandin E content in mucosa. It is recommended that in the treatment process of patients with gastric ulcer, they should stay away from smoking places, as much as possible avoid the hazards of passive smoking.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Shu Jing
AU  - Wei Sun
AU  - Weihai Jiang
PY  - 2015/07
DA  - 2015/07
TI  - Effects of Smoking on Rat Peptic Ulcer
BT  - Proceedings of the 3rd International Conference on Advances in Energy and Environmental Science 2015
PB  - Atlantis Press
SP  - 644
EP  - 647
SN  - 2352-5401
UR  - https://doi.org/10.2991/icaees-15.2015.118
DO  - 10.2991/icaees-15.2015.118
ID  - Jing2015/07
ER  -