Preparation of Simvastatin Loaded TiO2 nanotube arrays and its release behavior

DOI

10.2991/emeit.2012.248How to use a DOI?

Keywords

TiO2 nanotube array, simvastatin, release

Abstract

TiO2 nanotube array fabricated by anodization has large specific surface area and good biocompatibility. The simvastatin (SIM), which can promote bone formation, were filled into the TiO2 nanotube by using step concentration soaking method(SCS).The morphology of TiO2 nanotube arrays were observed by scanning electronic microscope, and the drug release in phosphate buffer solution (PBS) were determined by visible ultraviolet spectrophotometer. The results show that the simvatatin has been loaded into the TiO2 nanotube arrays, and could sustain release 15 days.

Copyright

© 2012, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Haizhen Tang
AU  - Xiufeng Xiao
AU  - Yirong Chen
AU  - Rongfang Liu
PY  - 2012/09
DA  - 2012/09
TI  - Preparation of Simvastatin Loaded TiO2 nanotube arrays and its release behavior
BT  - Proceedings of the 2nd International Conference on Electronic & Mechanical Engineering and Information Technology (EMEIT 2012)
PB  - Atlantis Press
SP  - 1138
EP  - 1141
SN  - 1951-6851
UR  - https://doi.org/10.2991/emeit.2012.248
DO  - 10.2991/emeit.2012.248
ID  - Tang2012/09
ER  -