Proceedings of the Conference on Health and Wellbeing in Modern Society (CHW 2021)

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Diagnostic and Treatment Difficulties of Autoimmune Hepatitis on Systemic Lupus Erythematosus. Case Study

Authors
Egor Ignatiev1, Diana Solovieva2, Elena Popova3, *, Natalya Arkhipova4
1North-Eastern Federal University named after M.K. Ammosov, 678281, Russia
2North-Eastern Federal University named after M.K. Ammosov, 678380, Russia
3North-Eastern Federal University named after M.K. Ammosova, 677010, Russia
4Republican Hospital № 1 – National Center of Medicine, 677010, Russia
*Corresponding author. Email: popova.e.k@empl.s-vfu.ru
Corresponding Author
Elena Popova
Available Online 17 January 2022.
DOI
10.2991/ahsr.k.220103.023How to use a DOI?
Keywords
autoimmune disorders; AIH; SLE; autoimmune hepatitis; systemic lupus erythematosus; immune-mediated combination
Abstract

On the example of case study, we present the features of the course of AIH on the background of SLE, as well as the difficulties of diagnosis and treatment. The study revealed an immune-mediated combination of autoimmune hepatitis with systemic lupus erythematosus, based on the association of autoimmune disorders with the main complex of human histocompatibility. The literature lacks data on the features of the course and treatment of comorbid patients with these pathologies. Autoimmune hepatitis on the background of systemic lupus erythematosus is characterized by early manifestation of the clinical picture, rapid progression of acute liver failure. The identification of immunological markers is diagnostically important; however, the morphological confirmation of the diagnosis is of paramount importance for deciding on the treatment. It should be borne in mind that AIH can proceed under the guise of other clinical signs for several years and can be mistakenly regarded as SLE, rheumatoid arthritis. Treatment involves a high risk of developing hepatic encephalopathy in response to pathogenetic therapy.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the Conference on Health and Wellbeing in Modern Society (CHW 2021)
Series
Advances in Health Sciences Research
Publication Date
17 January 2022
ISBN
978-94-6239-513-8
ISSN
2468-5739
DOI
10.2991/ahsr.k.220103.023How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - Egor Ignatiev
AU  - Diana Solovieva
AU  - Elena Popova
AU  - Natalya Arkhipova
PY  - 2022
DA  - 2022/01/17
TI  - Diagnostic and Treatment Difficulties of Autoimmune Hepatitis on Systemic Lupus Erythematosus. Case Study
BT  - Proceedings of the Conference on Health and Wellbeing in Modern Society (CHW 2021)
PB  - Atlantis Press
SP  - 113
EP  - 117
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220103.023
DO  - 10.2991/ahsr.k.220103.023
ID  - Ignatiev2022
ER  -