Research on Concanavalin A Crystallization in a Flow-Free Droplet-Based Device

DOI

10.2991/bbe-17.2017.70How to use a DOI?

Keywords

Protein, Crystallization, Droplet-based.

Abstract

Protein crystallography is a very critical process that limits the development of pharmaceutical engineering. Microfluidic technology has provided an opportunity for protein crystallization. In this paper, a flow-free droplet-based device is presented for producing highly controlled crystals and fabrication of this device with polydimethylsiloxane (PDMS) is presented. The experiment was performed on the device and shows that the crystals of Con A and protein ligand (DK3) have a spherical structure.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Guan-ru DU
AU  - Wen-jun ZHANG
AU  - Ding-kun JI
AU  - Feng-juan CHEN
AU  - Di YIN
AU  - Hong-bo ZHANG
AU  - Rui-xue YIN
AU  - Xiao-peng HE
AU  - Shih-Mo YANG
PY  - 2017/05
DA  - 2017/05
TI  - Research on Concanavalin A Crystallization in a Flow-Free Droplet-Based Device
BT  - Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
PB  - Atlantis Press
SP  - 435
EP  - 439
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-17.2017.70
DO  - 10.2991/bbe-17.2017.70
ID  - DU2017/05
ER  -