Design and Development of Long Range Surface Plasmon Resonance Sensor Chip and System for High Sensitivity Detection

DOI

10.2991/bbe-17.2017.45How to use a DOI?

Keywords

Surface plasmon resonance (SPR), Long range, Sensitivity, Biosensor.

Abstract

Long range surface plasmon resonance (LRSPR) was used to improve the propagation lengths, electric field strengths, and the sharpness of angular resonance curves compared with the conventional surface plasmon resonance (CSPR). LRSPR sensor chip was designed with buffer layer whose refractive indices in the vicinity of water. The resonance curves of the LRSPR and conventional SPR were compared under different parameters of multilayer structure by Winspall software. The theoretical calculation showed that the sensitivity of LRSPR method was higher than the conventional SPR. Homemade LRSPR sensor system was constructed with a red laser light source, a P-polarizer, a triangle glass prism, a long range sensor chip and a linear CCD detector. The performance of the LRSPR sensor were tested and compared. The results showed that the sensitivity of LRSPR chip was improved compared with the conventional SPR which was in accordance with the theoretical calculation. LRSPR showed a higher sensitivity and detection range so that it could be used as an excellent living cell sensing method for the real-time monitoring.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Lu-lu ZHANG
AU  - Xing CHEN
AU  - Cun-fang XU
AU  - Yan-fei REN
AU  - Ya-ting LI
AU  - Da-fu CUI
PY  - 2017/05
DA  - 2017/05
TI  - Design and Development of Long Range Surface Plasmon Resonance Sensor Chip and System for High Sensitivity Detection
BT  - Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
PB  - Atlantis Press
SP  - 270
EP  - 275
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-17.2017.45
DO  - 10.2991/bbe-17.2017.45
ID  - ZHANG2017/05
ER  -