Anti-Proliferative Activity of Benzamide Analogs in A549 Tumor Cells in Vitro

DOI

10.2991/bbe-17.2017.32How to use a DOI?

Keywords

Anti-Proliferative, Benzamide Analogs, A549, RTCA.

Abstract

Objective: To determine the antitumor activity of five benzamide derivatives with similar structure in A549 tumor cells. Methods: Cytotoxicity of the compounds in A549 tumor cells were monitored through an xCELLigence Real-Time Cell Analysis System. Results: Four benzamide analogs inhibited the growth of A549 tumor cells in a dose- and time-dependent manner. Conclusion: Four benzamideÿderivatives exhibited antiproliferative activity against A549 tumor cells in vitro and could be further developed in preclinical studies as therapeutic agents for non small cell lung cancer.

Copyright

© 2017, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Li-wen SHEN
AU  - Yan-ling WU
AU  - Min CHEN
AU  - Yoshimasa Tanaka
AU  - Wen ZHANG
PY  - 2017/05
DA  - 2017/05
TI  - Anti-Proliferative Activity of Benzamide Analogs in A549 Tumor Cells in Vitro
BT  - Proceedings of the 2nd International Conference on Biomedical and Biological Engineering 2017 (BBE 2017)
PB  - Atlantis Press
SP  - 198
EP  - 202
SN  - 2468-5747
UR  - https://doi.org/10.2991/bbe-17.2017.32
DO  - 10.2991/bbe-17.2017.32
ID  - SHEN2017/05
ER  -