Protective Effect of Natural Flavonoid Quercetin Against Exercise-induced Oxidative Damage in Experimental Rat Model

DOI

10.2991/aeece-15.2015.149How to use a DOI?

Keywords

quercetin; oxidative damage; exhaustive treadmill exercise; rat

Abstract

This study was conducted to investigate the effect of natural flavonoid quercetin on exercise-induced oxidative damage. Twenty-eight rats were randomly divided into four groups, a control and three quercetin administered groups (20, 40 and 60 mg/kg). Quercetin was orally administered to rats once a day for 28 days, followed by the exhaustive treadmill exercise. The results show that quercetin prolonged the running time to exhaustion of rats, as well as decreasing the levels of lactate dehydrogenase and creatine kinase in serun, and the levels of myeloperoxidase, malondialdehyde and 8-hydroxy-2'-deoxyguanosine in liver and muscle. This indicated that quercetin has a protective effect on exercise-induced oxidative damage.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Weiqiang Zhang
PY  - 2015/09
DA  - 2015/09
TI  - Protective Effect of Natural Flavonoid Quercetin Against Exercise-induced Oxidative Damage in Experimental Rat Model
BT  - Proceedings of the International Conference on Advances in Energy, Environment and Chemical Engineering
PB  - Atlantis Press
SP  - 735
EP  - 738
SN  - 2352-5401
UR  - https://doi.org/10.2991/aeece-15.2015.149
DO  - 10.2991/aeece-15.2015.149
ID  - Zhang2015/09
ER  -