Dr. Sulaiman Al Habib Medical Journal

Volume 3, Issue 2, June 2021, Pages 60 - 65

Is a History of Type 1 Allergic Diseases Associated with the Risk of Developing Multiple Sclerosis?

Authors
Abdulrahman Alfawzan1, *, ORCID, Saeed Alshahrani1, Ahmad Alswaidan1, Ala Alkharaan1, Hayyaf Aldossary2, Awad Almuklass2
1College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
2College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia; King Abdullah International Medical Research Center (KAIMRC), Riyadh, Saudi Arabia
*Corresponding author. Email: alfawzan.job@gmail.com
Corresponding Author
Abdulrahman Alfawzan
Received 25 October 2020, Accepted 31 January 2021, Available Online 19 February 2021.
DOI
10.2991/dsahmj.k.210210.001How to use a DOI?
Keywords
Multiple sclerosis; allergy type 1; hypersensitivity; atopy; allergic diseases
Abstract

Multiple Sclerosis (MS) is an autoimmune disorder affecting the central nervous system, characterized by demyelination of the neurons with limited remyelination. There has been a rising trend toward associating a history of allergy with MS. Both MS and type 1 allergies are developed by a hyper-reactive immune system. This is further reinforced by the similar environmental and genetic factors of both diseases. This review examines the association between a history of type 1 allergic diseases and the risk of MS, as well as the influence of study location on the association. A literature search was conducted through the Saudi Digital Library search engine, which includes many databases, such as PubMed and Web of Science; articles addressing the relationship between MS and type 1 allergies were retrieved. In this review, most studies show an inverse or no association between type 1 allergy history and MS. Most articles concluded that the relationship is not statistically significant. One study stated that asthma increases MS risk. Geographical location does not influence MS and allergy association.

Copyright
© 2021 Dr. Sulaiman Al Habib Medical Group. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Dr. Sulaiman Al Habib Medical Journal
Volume-Issue
3 - 2
Pages
60 - 65
Publication Date
2021/02/19
ISSN (Online)
2590-3349
ISSN (Print)
2666-819X
DOI
10.2991/dsahmj.k.210210.001How to use a DOI?
Copyright
© 2021 Dr. Sulaiman Al Habib Medical Group. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Abdulrahman Alfawzan
AU  - Saeed Alshahrani
AU  - Ahmad Alswaidan
AU  - Ala Alkharaan
AU  - Hayyaf Aldossary
AU  - Awad Almuklass
PY  - 2021
DA  - 2021/02/19
TI  - Is a History of Type 1 Allergic Diseases Associated with the Risk of Developing Multiple Sclerosis?
JO  - Dr. Sulaiman Al Habib Medical Journal
SP  - 60
EP  - 65
VL  - 3
IS  - 2
SN  - 2590-3349
UR  - https://doi.org/10.2991/dsahmj.k.210210.001
DO  - 10.2991/dsahmj.k.210210.001
ID  - Alfawzan2021
ER  -