Artery Research

Endothelial nitric oxide synthase (eNOS) is the main source of nitric oxide (NO) in the vascular wall, a molecule with anti-inflammatory, antithrombotic, vasorelaxant, antioxidant and finally antiatherogenic properties. eNOS is expressed in vascular endothelium, and it uses l-arginine as a substrate,...

Objective: A systematic histological, morphometric and immunohistochemical (PAI-1 and TGF-β1) study of umbilical vessels in normal and pathological conditions was undertaken in order to describe and compare the lesions found. Methods: Segments of umbilical cords were obtained from 92 pregnancies/107...

Background: Vasodilation of the peripheral arteries after reactive hyperaemia depends in part on the release of nitric oxide from endothelial cells. Previous studies mainly employed a fingertip tonometric device to derive pulse wave amplitude (PWA) and, therefore, measure PWA hyperaemic changes. Another...

Background: Arterial stiffness is a well-established indicator of cardiovascular disease outcome. Pulse Wave Velocity (PWV) is a surrogate for arterial stiffness that is measured either globally using carotid-to-femoral applanation tonometry or locally using biomedical imaging methods. Pulse Wave Imaging...

Background: To our knowledge, no previous study assessed the reproducibility of non-mydriatic imaging of retinal microvessels using state-of-the-art Bland and Altman statistics. Methods: In 194 subjects randomly selected from a Flemish population, we post-processed retinal images (Canon Cr-DGi) using...