Artery Research

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Volume 7, Issue 3-4, September 2013, Pages 158 - 158

P6.15 HAEMODYNAMIC-MECHANICAL INTERACTION IN TYPE-B AORTIC DISSECTION: EXPERIMENTAL AND COMPUTER MODEL STUDY

Authors
P.A. Rudenick1, B.H. Bijnens2, P. Segers3, D. García-Dorado1, A. Evangelista1
1University Hospital and Research Institute Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain
2ICREA, Physense – N-RAS, Universitat Pompeu Fabra, Barcelona, Spain
3Biofluid, Tissue and Solid Mechanics for Medical Applications, Institute Biomedical Technology, Ghent University, Ghent, Belgium
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.196How to use a DOI?
Abstract

Background: Type-B aortic dissections (TBADs) show a high morbidity and mortality in the long-term follow up. The role of and interaction between haemodynamics (pressure and flows), mechanics (wall compliance) and morphology (communication between false lumen (FL) and true lumen (TL)) is poorly understood, as well as the potential role of these variables in the outcome of TBADs.

Materials and methods: We developed both a hydraulic bench (experimental) and an electrical analogue model of a TBAD (Fig. 1). The model was calibrated and validated for eight experimental cases consisting of various permutations of proximal and distal tear sizes (no tear, 4 and 10 mm).

Results: The computer model was able to reproduce measured intraluminal pressures and velocities across tears with good agreement for all combinations (Fig. 2). Tear size is the major determinant of interaction between FL and TL. Tear sizes of 4 mm are associated with a reduced pressure in the FL, and strong oscillatory flow exchange between TL and FL. A tear size of 10 mm increases FL pressure to the same level or beyond TL pressures, and reduces the oscillatory nature of the flow.

Conclusions: Both the experimental and computer model reveal a complex dynamic interaction between TL and FL, modulated by the size and combination of the tears.

Figure 1

Electrical analogue model of a type-B aortic dissection

Figure 2

Comparison between predicted and experimental intraluminal pressures and velocities across tear

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
158 - 158
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.196How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - P.A. Rudenick
AU  - B.H. Bijnens
AU  - P. Segers
AU  - D. García-Dorado
AU  - A. Evangelista
PY  - 2013
DA  - 2013/11/11
TI  - P6.15 HAEMODYNAMIC-MECHANICAL INTERACTION IN TYPE-B AORTIC DISSECTION: EXPERIMENTAL AND COMPUTER MODEL STUDY
JO  - Artery Research
SP  - 158
EP  - 158
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.196
DO  - 10.1016/j.artres.2013.10.196
ID  - Rudenick2013
ER  -