Artery Research

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Volume 7, Issue 3-4, September 2013, Pages 150 - 151

P5.26 24 HOURS PULSATILE HEMODYNAMICS IN BORDERLINE VERSUS RESISTANT HYPERTENSIVES

Authors
T. Weber1, B. Hametner2, B. Eber1, S. Wassertheurer2
1Cardiology Department, Klinikum Wels-Grieskirchen, Wels, Austria
2Health & Environment Department, AIT Austrian Institute of Technology, Vienna, Austria
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.174How to use a DOI?
Abstract

Background: Diurnal variations of brachial blood pressure have important prognostic implications. The aim of this study was to investigate differences in day- and night-time values of brachial and central hemodynamic parameters in two groups of borderline and resistant hypertensives.

Methods: We performed 24 hour pulse wave analysis, using a brachial cuff and validated ARCSolver algorithms. Central pressures were derived with a generalized transfer function using measured mean and diastolic pressure for calibration. 50 borderline hypertensives (BH; mean age: 52 years, mean 24h brachial blood pressure (bBP): 123/81 mmHg) and 25 resistant hypertensives (RH; mean age: 58 years, mean 24h bBP: 138/85 mmHg) were included in the study. Day-time was specified as 09:00–21:00 and night-time as 01:00–06:00.

Results: With respect to bSBP, we observed a dipping phenomenon (decrease > 10%) in BH, but not in RH. In contrast, with respect to cSBP, no dipping was present in both groups, respectively. Heart rate was significantly lower at night-time in both groups. Daytime and night-time bPP did not differ in both groups, but cPP showed an increase at night-time in both groups. All measures of wave reflection increased at night-time in both groups.

Conclusions: Measuring 24h pulsatile central hemodynamic parameters using a cuff device is feasible and can lead to novel insights compared to brachial BP. Further studies should investigate the clinical value.

BH RH
Brachial systolic BP (mmHg) Day 127* 139$
Night 113 135$
Central systolic BP (mmHg) Day 128 144$
Night 123 147$
Brachial pulse pressure (mmHg) Day 41 51$
Night 40 54$
Central pulse pressure (mmHg) Day 41* 54$
Night 49 64$
Heart rate (bpm) Day 72* 69*
Night 59 60
AIx Day 23* 29*$
Night 29 38$
AIx@75 Day 22 25*
Night 20 30$
Amplitude backward wave (mmHg) Day 16* 22*$
Night 21 28$
Reflection magnitude Day 61* 64*
Night 70 71
*

p<0.05 day vs night;

$

p<0.05 BH vs RH.

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<Previous Article In Issue
Next Article In Issue>
Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
150 - 151
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.174How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - T. Weber
AU  - B. Hametner
AU  - B. Eber
AU  - S. Wassertheurer
PY  - 2013
DA  - 2013/11/11
TI  - P5.26 24 HOURS PULSATILE HEMODYNAMICS IN BORDERLINE VERSUS RESISTANT HYPERTENSIVES
JO  - Artery Research
SP  - 150
EP  - 151
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.174
DO  - 10.1016/j.artres.2013.10.174
ID  - Weber2013
ER  -