P3.25 THE EFFECT OF DIASTOLIC ASYMPTOTIC PRESSURE ON THE RESERVOIR PRESSURE IN HUMAN

DOI

10.1016/j.artres.2013.10.112How to use a DOI?

Abstract

Background: Arterial diastolic asymptotic pressure (P_∞) is the pressure reached when the heart stops beating. Determination of the reservoir pressure (P_r) requires a value of P_∞ which was previously assumed (1), calculated (2) and measured (3, 4) as 0, 35, 14, 24 mmHg respectively. The effects of varying P_∞ on the determination of P_r is the primary objective of this study.

Methods: P_r was calculated from the carotid pressure of 2003 subjects of the Asklepios study (a) using a free fitting algorithm for the determination of P_∞ and (b) setting P_∞ to the average of the experimental values (19 mmHg).

Results: The reservoir pulse pressure (PP_r) is higher using the free fitting method than setting P_∞ (Fig1). PP_r increases significantly with age and is higher in male than female in both cases.

Conclusions: PP_r is generally higher in male than female and its absolute value is dependant on the value of P_∞. Higher values of PP_r suggests deterioration of the arterial buffering function with age.

Figure 1.

Changes of PP_r with age and gender using the free fitting algorithm (a) and 19mmHg (b).

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TY  - JOUR
AU  - A. Borlotti
AU  - S. Vermeersch
AU  - E.R. Rietzschel
AU  - P. Segers
AU  - A.W. Khir
PY  - 2013
DA  - 2013/11/11
TI  - P3.25 THE EFFECT OF DIASTOLIC ASYMPTOTIC PRESSURE ON THE RESERVOIR PRESSURE IN HUMAN
JO  - Artery Research
SP  - 133
EP  - 133
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.112
DO  - 10.1016/j.artres.2013.10.112
ID  - Borlotti2013
ER  -