Artery Research

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Volume 7, Issue 3-4, September 2013, Pages 128 - 128

P3.07 THE ASSOCIATION BETWEEN LOW BODY MASS INDEX AND ARTERIAL STIFFNESS IN AFRICANS: THE PURE STUDY

Authors
H.W. Huisman, J.M. Van Rooyen, H.L. Venter, A.E. Schutte, R. Schutte, C.M.T. Fourie, C.M.C. Mels, W. Smith, N.T. Malan, L. Malan
North-West University Potchefstroom Campus, Potchefstroom, South Africa
Available Online 11 November 2013.
DOI
10.1016/j.artres.2013.10.095How to use a DOI?
Abstract

Objectives: In developing countries, urbanization leads to changes in behavioural lifestyle and malnutrition which may lead to higher rates of cardiovascular disease .1,2 We aimed to assess the association between low body mass index and markers of cardiovascular function like pulse wave velocity in Africans.

Methods: We included 496 Africans, aged between 35–65 years, with a low socio-economic status. They were stratified into a low BMI group with BMI ≤ 20 kg/m2 and a normal BMI group with BMI ≤ 20 kg/m2 and ≤ 25 kg/m2. Blood pressure (OMRON HEM-757) and PWV (Complier SP) were recorded.

Results: African men with low BMI revealed significantly higher DBP (88.0 ± 13.4 mm/Hg) compared to the normal BMI group (84.2 ± 12.2 mm/Hg) and an increased arterial stiffness with significantly higher PWV (12.6 ± 2.47 m/s) compared to the normal BMI group (11.6 ± 2.00 m/s). The significant higher DBP and PWV remained after adjusting for confounders. The BMI scatter plot illustrated a negative tendency towards PWV in Africans (r= −0.28; p<0.001). This negative association between PWV and BMI in African men was confirmed with regression analysis. When adjusting for age, smoking, alcohol intake, BP and heart rate a J-curve was evident between PWV and BMI.

Conclusion: This indicates a detrimental effect of low BMI on vascular function which may contributes to the high prevalence of CVD and mortality in Africans.

Open Access
This is an open access article distributed under the CC BY-NC license.

References

1.DB Pangiotakos et al., Public Health Nutr, Vol. 11, 2008, pp. 1342-1349.
2.M Hamer et al., Nutrition, Met & Cardio Diseases, Vol. 20, 2010, pp. 491-497.
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Journal
Artery Research
Volume-Issue
7 - 3-4
Pages
128 - 128
Publication Date
2013/11/11
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2013.10.095How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - H.W. Huisman
AU  - J.M. Van Rooyen
AU  - H.L. Venter
AU  - A.E. Schutte
AU  - R. Schutte
AU  - C.M.T. Fourie
AU  - C.M.C. Mels
AU  - W. Smith
AU  - N.T. Malan
AU  - L. Malan
PY  - 2013
DA  - 2013/11/11
TI  - P3.07 THE ASSOCIATION BETWEEN LOW BODY MASS INDEX AND ARTERIAL STIFFNESS IN AFRICANS: THE PURE STUDY
JO  - Artery Research
SP  - 128
EP  - 128
VL  - 7
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2013.10.095
DO  - 10.1016/j.artres.2013.10.095
ID  - Huisman2013
ER  -