P60 Invasive Validation of Antares, a New Algorithm to Calculate Central Blood Pressure from Oscillometric Upper Arm Pulse Waves

Marcus Doerr; Stefan Richter; Siegfried Eckert; Marc-Alexander Ohlow; Fabian Hammer; Astrid Hummel; Vivien Dornberger; Elisabeth Genzel; Johannes Baulmann

doi:10.2991/artres.k.191224.091

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Volume 25, Issue Supplement 1, December 2019, Pages S101 - S101

P60 Invasive Validation of Antares, a New Algorithm to Calculate Central Blood Pressure from Oscillometric Upper Arm Pulse Waves

Authors

Marcus Doerr¹^{, 2}, Stefan Richter³, Siegfried Eckert⁴, Marc-Alexander Ohlow³, Fabian Hammer¹, Astrid Hummel¹, Vivien Dornberger¹, Elisabeth Genzel¹, Johannes Baulmann⁵^{, 6}^{, *}

¹Department of Internal Medicine B, University Medicine Greifswald, Germany

²German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Germany

³Zentralklinik Bad Berka GmbH, Herzzentrum, Department of Cardiology, Germany

⁴Klinik für Allgemeine und Interventionelle Kardiologie/Angiologie, Universitätsklinik der Ruhr-Universität Bochum, Bad Oeynhausen, Germany

⁵Medizinische Universität Graz, Austria

⁶European Prevention Center, Düsseldorf, Germany

^*Corresponding author. Email: jbaulmann@yahoo.com

Corresponding Author

Johannes Baulmann

Available Online 17 February 2020.

DOI: 10.2991/artres.k.191224.091 How to use a DOI?
Abstract: Background: Antares is an algorithm for pulse wave analysis (PWA) by oscillometric blood pressure monitors in order to estimate central (aortic) blood pressure (cBP). Antares aims to enable brachial cuff-based blood pressure (BP) monitors to be type II-devices, determining absolute cBP values independently of potential peripheral BP inaccuracies. The present study is an invasive validation of the Antares algorithm.

Methods: We followed entirely the 2017 ARTERY protocol for validation of non-invasive cBP devices, the 2013 ANSI/AAMI/ISO 81060-2 and 2018 AAMI/ESH/ISO validation standard protocols. In total, 191 patients undergoing cardiac catheterization were included, of which 145 patients entered analysis. Invasive cBP recordings were prospectively compared to simultaneous non-invasive cBP estimations using Antares, integrated into an oscillometric BP monitor. Antares analyses pulse waves during deflation of the cuff (patent of Redwave Medical GmbH). Generally speaking, pulse waves of a normal oscillometric BP measurement are taken for PWA with no need for altering standard BP pump operation.

Results: Mean difference between invasive and non-invasively estimated systolic cBP was 0.71 mmHg with standard deviation of 5.95 mmHg, fulfilling the highest validation criteria. Bland-Altman plot reveals good limits of agreement.

Conclusion: Antares is the first algorithm for estimation of cBP that entirely fulfills the 2017 ARTERY and AAMI/ESH/ISO validation protocols including criteria for high accuracy devices. The Antares algorithm turns the oscillometric upper arm blood pressure monitor into a type II-device for estimation of true cBP. Integration of Antares into BP monitors could enable the measurement of PWA parameters in virtually every practice in future.
Open Access: This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal: Artery Research
Volume-Issue: 25 - Supplement 1
Pages: S101 - S101
Publication Date: 2020/02/17
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.2991/artres.k.191224.091 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

ris enw bib

TY  - JOUR
AU  - Marcus Doerr
AU  - Stefan Richter
AU  - Siegfried Eckert
AU  - Marc-Alexander Ohlow
AU  - Fabian Hammer
AU  - Astrid Hummel
AU  - Vivien Dornberger
AU  - Elisabeth Genzel
AU  - Johannes Baulmann
PY  - 2020
DA  - 2020/02/17
TI  - P60 Invasive Validation of Antares, a New Algorithm to Calculate Central Blood Pressure from Oscillometric Upper Arm Pulse Waves
JO  - Artery Research
SP  - S101
EP  - S101
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.091
DO  - 10.2991/artres.k.191224.091
ID  - Doerr2020
ER  -

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