Artery Research

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Volume 12, Issue C, December 2015, Pages 25 - 25

P6.1 DIURNAL CHANGES IN PULSE PRESSURE AMPLIFICATION IN NORMOTENSIVE, HYPERTENSIVE DIPPER AND HYPERTENSIVE NON-DIPPER PATIENTS

Authors
Sandrine Millasseau1, Yulia Kotovskaya2, Jirar Topouchian3, Igor Posokhov*4
1Pulse Wave Consulting, Saint Leu la Foret, France
2Russian Peoples Friendship University, Moscow, Russia
3Diagnostic and Therapeutic Center, Hotel Dieu Hospital, Paris, France
4Hemodynamic Laboratory Ltd, Nizhny Novgorod, Russia
Available Online 23 November 2015.
DOI
10.1016/j.artres.2015.10.285How to use a DOI?
Abstract

Office central blood pressure (cBP) have been shown to better predict cardiovascular events than standard peripheral pressure. With Vasotens software and BPLab monitor (OOO Petr Telegin, Russia) is now possible to estimate central pressure over 24h. However to date, no data have shown that 24h monitoring cBP have added value to office measurements. We looked at diurnal changes in pulse pressure amplification (PPamp=peripheral pulse pressure/ central pulse pressure) cBP and PWV in 120(60M/60F) normotensives (NT), 120(60M/60F) hypertensive dippers (DI) and 120(60M/60F) hypertensive non-dippers(ND) matched for age, sex and day brachial SBP for the hypertensive subjects.

Between day and night, peripheral systolic blood pressure fell from 122±8 to 103±7, from 140±11 to 117±11 and from 140±12 to 137±14mmHg in NT, DI and ND respectively. Heart rate fell from 70±8 to 59±7bpm in NT, from 77±10 to 63±8bpm in DI and from 73±12 to 65±11bpm in ND. Day PPamp was slightly higher in DI than other groups (132±7%, 135±8%, 131±9% in NT, DI and ND respectively, p<0.001 ANOVA). Night PPamp was lower but did not vary between groups (123±7%, 124±6% and 123±7%, p=0,11). However PPamp was correlated with HR (R2=0,36). After correction for HR changes, PPamp did not differ during day and night.

Once corrected for HR, diurnal variations of central pressure seems to be in parallel to peripheral blood pressure whatever is the hypertensive or dipping status.

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Journal
Artery Research
Volume-Issue
12 - C
Pages
25 - 25
Publication Date
2015/11/23
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2015.10.285How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Sandrine Millasseau
AU  - Yulia Kotovskaya
AU  - Jirar Topouchian
AU  - Igor Posokhov*
PY  - 2015
DA  - 2015/11/23
TI  - P6.1 DIURNAL CHANGES IN PULSE PRESSURE AMPLIFICATION IN NORMOTENSIVE, HYPERTENSIVE DIPPER AND HYPERTENSIVE NON-DIPPER PATIENTS
JO  - Artery Research
SP  - 25
EP  - 25
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.285
DO  - 10.1016/j.artres.2015.10.285
ID  - Millasseau2015
ER  -