P6.1 DIURNAL CHANGES IN PULSE PRESSURE AMPLIFICATION IN NORMOTENSIVE, HYPERTENSIVE DIPPER AND HYPERTENSIVE NON-DIPPER PATIENTS

Sandrine Millasseau; Yulia Kotovskaya; Jirar Topouchian; Igor Posokhov*

doi:10.1016/j.artres.2015.10.285

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Volume 12, Issue C, December 2015, Pages 25 - 25

P6.1 DIURNAL CHANGES IN PULSE PRESSURE AMPLIFICATION IN NORMOTENSIVE, HYPERTENSIVE DIPPER AND HYPERTENSIVE NON-DIPPER PATIENTS

Authors

Sandrine Millasseau¹, Yulia Kotovskaya², Jirar Topouchian³, Igor Posokhov*⁴

¹Pulse Wave Consulting, Saint Leu la Foret, France

²Russian Peoples Friendship University, Moscow, Russia

³Diagnostic and Therapeutic Center, Hotel Dieu Hospital, Paris, France

⁴Hemodynamic Laboratory Ltd, Nizhny Novgorod, Russia

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.285 How to use a DOI?
Abstract: Office central blood pressure (cBP) have been shown to better predict cardiovascular events than standard peripheral pressure. With Vasotens software and BPLab monitor (OOO Petr Telegin, Russia) is now possible to estimate central pressure over 24h. However to date, no data have shown that 24h monitoring cBP have added value to office measurements. We looked at diurnal changes in pulse pressure amplification (PPamp=peripheral pulse pressure/ central pulse pressure) cBP and PWV in 120(60M/60F) normotensives (NT), 120(60M/60F) hypertensive dippers (DI) and 120(60M/60F) hypertensive non-dippers(ND) matched for age, sex and day brachial SBP for the hypertensive subjects.

Between day and night, peripheral systolic blood pressure fell from 122±8 to 103±7, from 140±11 to 117±11 and from 140±12 to 137±14mmHg in NT, DI and ND respectively. Heart rate fell from 70±8 to 59±7bpm in NT, from 77±10 to 63±8bpm in DI and from 73±12 to 65±11bpm in ND. Day PPamp was slightly higher in DI than other groups (132±7%, 135±8%, 131±9% in NT, DI and ND respectively, p<0.001 ANOVA). Night PPamp was lower but did not vary between groups (123±7%, 124±6% and 123±7%, p=0,11). However PPamp was correlated with HR (R2=0,36). After correction for HR changes, PPamp did not differ during day and night.

Once corrected for HR, diurnal variations of central pressure seems to be in parallel to peripheral blood pressure whatever is the hypertensive or dipping status.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 12 - C
Pages: 25 - 25
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.285 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Sandrine Millasseau
AU  - Yulia Kotovskaya
AU  - Jirar Topouchian
AU  - Igor Posokhov*
PY  - 2015
DA  - 2015/11/23
TI  - P6.1 DIURNAL CHANGES IN PULSE PRESSURE AMPLIFICATION IN NORMOTENSIVE, HYPERTENSIVE DIPPER AND HYPERTENSIVE NON-DIPPER PATIENTS
JO  - Artery Research
SP  - 25
EP  - 25
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.285
DO  - 10.1016/j.artres.2015.10.285
ID  - Millasseau2015
ER  -

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