P4.3 PHYSICAL ACTIVITY IS ASSOCIATED WITH LOWER ARTERIAL STIFFNESS IN OLDER ADULTS: RESULTS OF THE SAPALDIA 3 COHORT STUDY
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- 10.1016/j.artres.2015.10.247How to use a DOI?
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We examined cross-sectional associations of self-reported PA intensities with arterial stiffness in elderly Caucasians of the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). Mixed central and peripheral arterial stiffness was measured oscillometrically by the cardio-ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV). The self-reported International Physical Activity Questionnaire (IPAQ) long version was administered to classify each subject’s PA level. We used univariable and multivariable mixed linear and logistic regression models for analyses in 1908 persons aged 50 years and older. After adjustment for several confounders moderate, vigorous and total PA were inversely associated with CAVI (p=0.02–0.03). BaPWV showed negative and marginally significant associations with vigorous and moderate PA (each p=0.06), but not with total PA (p=0.28). Increased arterial stiffness (CAVI≥9, upper tertile) was inversely and significantly associated with vigorous PA (Odds Ratio (OR)=0.65, 95% Confidence Interval (CI): 0.48–0.88), and marginally significantly with total PA (OR=0.76, 95% CI: 0.57–1.02) and moderate PA (OR=0.75, 95% CI: 0.56–1.01). The odds ratio for baPWV≥14.4 was 0.67 (95% CI: 0.48–0.93) across the vigorous PA levels, and was non-significant across the total (OR=0.91, 95% CI: 0.66–1.23) and moderate PA levels (OR=0.94, 95% CI: 0.69–1.28). In this general Caucasian population of older adults higher levels especially of vigorous PA were associated with lower arterial stiffness. These data support the importance of PA for improving cardiovascular health in elderly people.
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TY - JOUR AU - Simon Endes* AU - Emmanuel Schaffner AU - Seraina Caviezel AU - Julia Dratva AU - Christine S. Autenrieth AU - Miriam Wanner AU - Brian Martin AU - Daiana Stolz AU - Marco Pons AU - Alexander Turk AU - Robert Bettschart AU - Christian Schindler AU - Nino Künzli AU - Nicole Probst-Hensch AU - Arno Schmidt-Trucksäss PY - 2015 DA - 2015/11/23 TI - P4.3 PHYSICAL ACTIVITY IS ASSOCIATED WITH LOWER ARTERIAL STIFFNESS IN OLDER ADULTS: RESULTS OF THE SAPALDIA 3 COHORT STUDY JO - Artery Research SP - 15 EP - 16 VL - 12 IS - C SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2015.10.247 DO - 10.1016/j.artres.2015.10.247 ID - Endes*2015 ER -