P4.3 PHYSICAL ACTIVITY IS ASSOCIATED WITH LOWER ARTERIAL STIFFNESS IN OLDER ADULTS: RESULTS OF THE SAPALDIA 3 COHORT STUDY

Simon Endes*; Emmanuel Schaffner; Seraina Caviezel; Julia Dratva; Christine S. Autenrieth; Miriam Wanner; Brian Martin; Daiana Stolz; Marco Pons; Alexander Turk; Robert Bettschart; Christian Schindler; Nino Künzli; Nicole Probst-Hensch; Arno Schmidt-Trucksäss

doi:10.1016/j.artres.2015.10.247

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Volume 12, Issue C, December 2015, Pages 15 - 16

P4.3 PHYSICAL ACTIVITY IS ASSOCIATED WITH LOWER ARTERIAL STIFFNESS IN OLDER ADULTS: RESULTS OF THE SAPALDIA 3 COHORT STUDY

Authors

Simon Endes*¹, Emmanuel Schaffner²^{, 3}, Seraina Caviezel²^{, 3}, Julia Dratva²^{, 3}, Christine S. Autenrieth²^{, 3}, Miriam Wanner⁴, Brian Martin⁴, Daiana Stolz⁵, Marco Pons⁶, Alexander Turk⁷, Robert Bettschart⁸, Christian Schindler²^{, 3}, Nino Künzli²^{, 3}, Nicole Probst-Hensch²^{, 3}, Arno Schmidt-Trucksäss¹

¹Department of Sport, Exercise and Health, Div. Sports and Exercise Medicine, University of Basel, Basel, Switzerland

²Swiss Tropical and Public Health Institute, Basel, Switzerland

³University of Basel, Basel, Switzerland

⁴Physical Activity and Health Working Unit, Institute of Social and Preventive Medicine, University of Zurich, Zurich, Switzerland

⁵Clinic of Pneumology and Respiratory Cell Research, University Hospital, Basel, Switzerland

⁶Division of Pulmonary Medicine, Regional Hospital Lugano, Lugano, Switzerland

⁷Zürcher Höhenklinik, Wald-Faltigberg, Faltigberg-Wald, Switzerland

⁸Lungenpraxis Hirslanden Klinik Aarau, Aarau, Switzerland

Available Online 23 November 2015.

DOI: 10.1016/j.artres.2015.10.247 How to use a DOI?
Abstract: We examined cross-sectional associations of self-reported PA intensities with arterial stiffness in elderly Caucasians of the Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults (SAPALDIA). Mixed central and peripheral arterial stiffness was measured oscillometrically by the cardio-ankle vascular index (CAVI) and brachial-ankle pulse wave velocity (baPWV). The self-reported International Physical Activity Questionnaire (IPAQ) long version was administered to classify each subject’s PA level. We used univariable and multivariable mixed linear and logistic regression models for analyses in 1908 persons aged 50 years and older. After adjustment for several confounders moderate, vigorous and total PA were inversely associated with CAVI (p=0.02–0.03). BaPWV showed negative and marginally significant associations with vigorous and moderate PA (each p=0.06), but not with total PA (p=0.28). Increased arterial stiffness (CAVI≥9, upper tertile) was inversely and significantly associated with vigorous PA (Odds Ratio (OR)=0.65, 95% Confidence Interval (CI): 0.48–0.88), and marginally significantly with total PA (OR=0.76, 95% CI: 0.57–1.02) and moderate PA (OR=0.75, 95% CI: 0.56–1.01). The odds ratio for baPWV≥14.4 was 0.67 (95% CI: 0.48–0.93) across the vigorous PA levels, and was non-significant across the total (OR=0.91, 95% CI: 0.66–1.23) and moderate PA levels (OR=0.94, 95% CI: 0.69–1.28). In this general Caucasian population of older adults higher levels especially of vigorous PA were associated with lower arterial stiffness. These data support the importance of PA for improving cardiovascular health in elderly people.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 12 - C
Pages: 15 - 16
Publication Date: 2015/11/23
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2015.10.247 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

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ris enw bib

TY  - JOUR
AU  - Simon Endes*
AU  - Emmanuel Schaffner
AU  - Seraina Caviezel
AU  - Julia Dratva
AU  - Christine S. Autenrieth
AU  - Miriam Wanner
AU  - Brian Martin
AU  - Daiana Stolz
AU  - Marco Pons
AU  - Alexander Turk
AU  - Robert Bettschart
AU  - Christian Schindler
AU  - Nino Künzli
AU  - Nicole Probst-Hensch
AU  - Arno Schmidt-Trucksäss
PY  - 2015
DA  - 2015/11/23
TI  - P4.3 PHYSICAL ACTIVITY IS ASSOCIATED WITH LOWER ARTERIAL STIFFNESS IN OLDER ADULTS: RESULTS OF THE SAPALDIA 3 COHORT STUDY
JO  - Artery Research
SP  - 15
EP  - 16
VL  - 12
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2015.10.247
DO  - 10.1016/j.artres.2015.10.247
ID  - Endes*2015
ER  -

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