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Volume 16, Issue C, December 2016, Pages 95 - 96

PO-24 RELATIONSHIP BETWEEN STEP COUNTS AND CAROTID FEMORAL PULSE WAVE VELOCITY IN ADULTS TREATED FOR HYPERTENSION AND DIABETES

Authors
Kaberi Dasgupta2, 3, Alexandra B. Cooke1, Ellen Rosenberg4, Lawrence Joseph5, Stella S. Daskalopoulou1, 2
1Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, QC, Canada
2Division of Internal Medicine, Department of Medicine, McGill University Health Center, McGill University, Montreal, QC, Canada
3Division of Clinical Epidemiology, Department of Medicine, McGill University, Montreal, QC, Canada
4Department of Family Medicine, Department of Medicine, McGill University, Montreal, QC, Canada
5Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC, Canada
Available Online 24 November 2016.
DOI
10.1016/j.artres.2016.08.029How to use a DOI?
Abstract

Objectives: ‘Step counts’ captured by wearable physical activity tracking devices are associated with reductions in cardiovascular disease. However, in individuals on cardioprotective medications the impact of step counts may not be captured by the measurement of traditional cardiometabolic risk factors. To address this gap, we aimed to assess the relationship between pedometer-derived step counts and carotid-femoral pulse wave velocity (cfPWV), a summative measure of arterial health.

Methods: 369 adults (46% men, 60% White, mean age 59.6±11.2 years, BMI 31.3±4.5 kg/m2) with hypertension and/or type 2 diabetes were recruited in Montreal, Canada (2011–2015). Step counts (Yamax SW-701 pedometer), moderate-to-vigorous physical activity (MVPA) (ActiGraph GT3x+), arterial stiffness (applanation tonometry; SphygmoCor), and cardiometabolic risk factors including blood pressure, haemoglobin AIc, and lipids were assessed.

Results: Blood pressure was well-controlled (mean 125/77±15/9 mmHg), low-density lipoprotein cholesterol (LDL-C) was close to target (mean 2.5±1.0 mmol/L), and A1c in diabetes was acceptable (mean 7.7±1.3%). Participants averaged 5,125±2,722 steps/day (low active) and mean cfPWV was 9.8±2.2 m/s. Step counts correlated with cfPWV, but not with any other cardiometabolic risk factors. A 1,000 step/day increment was associated with a 0.1m/s (95% CI −0.19, −0.02) decrement in cfPWV in a model adjusted for age, sex, BMI, ethnicity, immigration status, employment, education, diabetes, hypertension, medication classes, and MVPA.

Conclusion: In patients with hypertension and/or diabetes who were well-controlled on cardioprotective medications, cfPWV is responsive to step counts and may emerge as a useful health indicator to track the arterial health impact of physical activity strategies in clinical practice.

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This is an open access article distributed under the CC BY-NC license.

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Journal
Artery Research
Volume-Issue
16 - C
Pages
95 - 96
Publication Date
2016/11/24
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2016.08.029How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Kaberi Dasgupta
AU  - Alexandra B. Cooke
AU  - Ellen Rosenberg
AU  - Lawrence Joseph
AU  - Stella S. Daskalopoulou
PY  - 2016
DA  - 2016/11/24
TI  - PO-24 RELATIONSHIP BETWEEN STEP COUNTS AND CAROTID FEMORAL PULSE WAVE VELOCITY IN ADULTS TREATED FOR HYPERTENSION AND DIABETES
JO  - Artery Research
SP  - 95
EP  - 96
VL  - 16
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2016.08.029
DO  - 10.1016/j.artres.2016.08.029
ID  - Dasgupta2016
ER  -