P2.05 INVESTIGATION OF FLOW AND WALL SHEAR STRESS DURING PULSATILE FLOW IN A HUMAN AORTA WITH A COARCTATION AND POST-STENOTIC DILATATION USING LARGE EDDY SIMULATIONS
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Flow field and wall shear stress (WSS) in an idealized model of a human aorta with a coarctation and a post-stenotic dilatation, Figure 1, were investigated with large eddy simulation. A physiologic pulse was prescribed at the inlet, Figure 1. Phase averages of axial WSS, from 30 consecutive pulses, were determined between the throat (x=0) and the exit (x=0.2 m) along lines where the x-y plane and x-z plane cross the vessel wall. Figure 2 shows these values at late systole; the pattern is representative for the entire systolic phase. WSS peaks in the stenosis, as expected, but also at the end of the dilatation (x=0.06 m). In the dilatation backflow causes a negative peak. Diastolic WSS is characterised by low amplitude oscillations. Also noticeable is the asymmetric pattern between the inner (y>0) and outer (y<0) sides caused by the flow through the arch. Thus, large spatial, temporal, and probably asymmetric WSS gradients in the already diseased region suggest increased risk for further endothelial dysfunction [1]. This reflects a complex, partly turbulent, flow pattern that may disturb the blood flow in the abdominal aorta.

Geometry with flow direction and inlet pulse profile.

Phase averaged axial WSS along four lines between the throat (x=0) and the exit (x=0.2 m).
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TY - JOUR AU - R. Gårdhagen AU - M. Karlsson PY - 2012 DA - 2012/11/17 TI - P2.05 INVESTIGATION OF FLOW AND WALL SHEAR STRESS DURING PULSATILE FLOW IN A HUMAN AORTA WITH A COARCTATION AND POST-STENOTIC DILATATION USING LARGE EDDY SIMULATIONS JO - Artery Research SP - 164 EP - 165 VL - 6 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2012.09.086 DO - 10.1016/j.artres.2012.09.086 ID - Gårdhagen2012 ER -