P2.05 INVESTIGATION OF FLOW AND WALL SHEAR STRESS DURING PULSATILE FLOW IN A HUMAN AORTA WITH A COARCTATION AND POST-STENOTIC DILATATION USING LARGE EDDY SIMULATIONS
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Flow field and wall shear stress (WSS) in an idealized model of a human aorta with a coarctation and a post-stenotic dilatation, Figure 1, were investigated with large eddy simulation. A physiologic pulse was prescribed at the inlet, Figure 1. Phase averages of axial WSS, from 30 consecutive pulses, were determined between the throat (x=0) and the exit (x=0.2 m) along lines where the x-y plane and x-z plane cross the vessel wall. Figure 2 shows these values at late systole; the pattern is representative for the entire systolic phase. WSS peaks in the stenosis, as expected, but also at the end of the dilatation (x=0.06 m). In the dilatation backflow causes a negative peak. Diastolic WSS is characterised by low amplitude oscillations. Also noticeable is the asymmetric pattern between the inner (y>0) and outer (y<0) sides caused by the flow through the arch. Thus, large spatial, temporal, and probably asymmetric WSS gradients in the already diseased region suggest increased risk for further endothelial dysfunction [1]. This reflects a complex, partly turbulent, flow pattern that may disturb the blood flow in the abdominal aorta.
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TY - JOUR AU - R. Gårdhagen AU - M. Karlsson PY - 2012 DA - 2012/11/17 TI - P2.05 INVESTIGATION OF FLOW AND WALL SHEAR STRESS DURING PULSATILE FLOW IN A HUMAN AORTA WITH A COARCTATION AND POST-STENOTIC DILATATION USING LARGE EDDY SIMULATIONS JO - Artery Research SP - 164 EP - 165 VL - 6 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2012.09.086 DO - 10.1016/j.artres.2012.09.086 ID - Gårdhagen2012 ER -