Artery Research

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Volume 6, Issue 4, December 2012, Pages 164 - 164

P2.04 PULSE WAVE VELOCITY AND WAVE INTENSITY IN THE CAROTID ARTERY OF HEALTHY HUMAN: WINDKESSEL AND WINDKESSEL-LESS ANALYSIS

Authors
A. Borlotti1, S. Vermeersch2, E.R. Rietzschel2, M.L. De Buyzere2, P. Segers2, A.W. Khir1
1Brunel University, London, United Kingdom
2Ghent University, Ghent, Belgium
Available Online 17 November 2012.
DOI
10.1016/j.artres.2012.09.085How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Pulse wave velocity (PWV) is an acknowledged marker to arterial compliance. A time-domain approach to study wave propagation taking into account the Windkessel effects in arteries was introduced (1). The model assumes that the measured pressure (P) and velocity (U) are the sum of two components; a reservoir (Pr, Ur) due to the buffering capacity of arteries and an excess (Pe, Ue) due to the waves. A direct comparison of PWV and wave intensity (WI) with and without considering Pr is lacking and quantifying the differences constitutes the objective of this work.

We measured P and U in the carotid artery of 328 healthy human subjects (45±6 years old); a subset of the Asklepios study to examine pulse velocity and intensity with (PWV and WI) and without (PWVe and WIe) the Windkessel effects.

PWV is 45% higher than PWVe (8.4±2.4 vs. 5.8±2.0 m/s, p<0.001). The intensities of the forward and backward compression waves of WI are 35% and 166% higher than those of WIe (21.8±8.0 vs. 16.2±7.1 W/m2 and 3.2±2.5 vs. 1.2±0.9 W/m2, p<0.001).

Values of pulse wave velocity and intensities vary massively depending on whether Pr is taken into account. A Pr independent methods for calculating these parameters are needed to determine the relative accuracy and importance of Pr.

Figure 1

Wave speed (left) and intensity (right) using the Windkessel and Windkessel-less analysis.

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Journal
Artery Research
Volume-Issue
6 - 4
Pages
164 - 164
Publication Date
2012/11/17
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2012.09.085How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - A. Borlotti
AU  - S. Vermeersch
AU  - E.R. Rietzschel
AU  - M.L. De Buyzere
AU  - P. Segers
AU  - A.W. Khir
PY  - 2012
DA  - 2012/11/17
TI  - P2.04 PULSE WAVE VELOCITY AND WAVE INTENSITY IN THE CAROTID ARTERY OF HEALTHY HUMAN: WINDKESSEL AND WINDKESSEL-LESS ANALYSIS
JO  - Artery Research
SP  - 164
EP  - 164
VL  - 6
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2012.09.085
DO  - 10.1016/j.artres.2012.09.085
ID  - Borlotti2012
ER  -