Artery Research

Volume 4, Issue 4, December 2010, Pages 186 - 186

P14.03 IS THERE A SHIFT OF THE REFLECTION POINT FROM PERIPHERAL TO CENTRAL ARTERIES WITH AGE IN HYPERTENSIVE PATIENTS?

Authors
P. Forcada1, D. Olano2, S. Gonzalez1, S. Obregon1, J. Chiavaut Svane1, C. Castelaro1, E. Cavanagh2, F. Inserra2, C. Kotliar1
1Hospital Universitario Austral, Pilar, Argentina
2Universidad Austral, Pilar, Argentina
Available Online 2 December 2010.
DOI
10.1016/j.artres.2010.10.144How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Introduction: Stiffening of arteries with age has been extensively described but this proccess has not been fully characterized at different levels of the arterial tree.

Aim: To evaluate the behavior of arterial function parameters according to age.

Methods: We screened 3277 p. derived for non-invasive vascular evaluation (NIVE) (Dec 2006/Dec 2009). NIVE comprised: IMT; PWV and FMD; atherosclerotic plaque (AP) characterization; Aortic and Peripheral pulse pressure(CPP and PPP) and Augmentation indexes (CAix and PAix). After applying exclusion criteria (age >65; diabetes mellitus, secondary HTN, previous CV events/secondary prevention) and the availability of data of PWV, CAix and PAix 1503 p. were included and analyzed according age (from 20 to 80 years old in deciles).

Results: We observed a progressive increase of all the arterial parameters with age (from 20 to 80 y.o.): PWV (8,8± 2 to 14± 4 m/sec), CPP (from 43± 15 to 59± 17mmHg), PPP (from 49± 12 to 58± 13 mmHg), CAix (from 12 to 36%) and PAix (from − 40% to 13%).

In the 50th decade a cross of values of PP (Central >Peripheral) and increase of PAix was observed suggesting a shift of the reflection point from peripheral to central arteries.

Conclusions: The stiffening of central arteries with age is associated with a progressive shift of the reflection point from peripheral to the central arteries and the loss of the pulse amplification in peripheral arteries.

Journal
Artery Research
Volume-Issue
4 - 4
Pages
186 - 186
Publication Date
2010/12/02
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2010.10.144How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

TY  - JOUR
AU  - P. Forcada
AU  - D. Olano
AU  - S. Gonzalez
AU  - S. Obregon
AU  - J. Chiavaut Svane
AU  - C. Castelaro
AU  - E. Cavanagh
AU  - F. Inserra
AU  - C. Kotliar
PY  - 2010
DA  - 2010/12/02
TI  - P14.03 IS THERE A SHIFT OF THE REFLECTION POINT FROM PERIPHERAL TO CENTRAL ARTERIES WITH AGE IN HYPERTENSIVE PATIENTS?
JO  - Artery Research
SP  - 186
EP  - 186
VL  - 4
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2010.10.144
DO  - 10.1016/j.artres.2010.10.144
ID  - Forcada2010
ER  -