The complex branching topology of the local vascular bed contributes to the complex nature of the blood pressure and flow in the human forearm. The aim of this work is to develop a full scale hydraulic bench model within the framework of our research into arterio-venous fistula creation and the relationship between blood pressure in the upper arm and the wrist. A silicon 3D-model of the brachial, ulnar, radial and anterior interosseous artery completed with the palmar arch was constructed in full scale. The geometry was based on patient-specific functional measurements and MR-data. The Patient-specific Arterial Model (PAM) was built in a mock loop consisting of an upstream reservoir, a pulsatile pump, a windkessel and variable resistances downstream (Figure). 7.5% of the blood mimicking fluid (water-glycerine mixture) was flowing to the interosseous, while the remaining was split equally over the four outflow paths in the palmar arch. Wave Intensity Analysis (WIA) was performed to assess wave reflection patterns in the model. A typical WIA pattern at the brachial inlet is shown in the figure. The initial forward compression wave (FCW) generated by the heart is distally reflected and returns as a backward compression wave (BCW), whereas the subsequent forward expansion wave (FEW) can be interpreted as the open end-type reflection of this BCW. The FEW is on his turn reflected downstream in the backward expansion wave (BEW). The in-vitro PAM shows the complexity of the wave reflections and will be used to study more specific flow problems in the forearm.