P2.11 IMAGING OF RETINAL ARTERIOLAR WALL IN VIVO IN HUMANS
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- 10.1016/j.artres.2011.10.032How to use a DOI?
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Purpose: Adaptive optics (AO) is an opto-electronic technique improving lateral resolution of fundus images. Here we report a novel application of AO imaging, namely the visualization of the arteriolar wall in the human retina.
Methods: This study was done in compliance with French ethical regulations. AO fundus imaging was performed using a prototypic camera (RTX1, ImagineEye, Orsay, France) in a cohort of healthy subjects and in patients affected by arterial hypertension. The camera uses infrared light, and the total acquisition time is less than 1 minute. The wall-to-lumen ratio (WLR) was measured in an arteriolar segment approximately 500 microns from the disc.
Results: 12 healthy subjects, 2 hypertensive patients and 1 patient affected by branch retinal vein occlusion were examined. The wall-to-lumen ratio varied from 11 to 15% in healthy eyes, and was 18% and 19% in the two hypertensive subjects. In the subject that had branch retinal vein occlusion, irregular thickening of the vessel wall was found.
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Conclusions: We provide here the first in vivo images of the arteriolar wall in humans. This technique may be useful for the quantitative assessment of microvascular damage in aged and/or hypertensive patients.
Funded by the Agence Nationale de la Recherche (TecSan 09-009)
Cite this article
TY - JOUR AU - M. Paques AU - K. Gocho-Nakashima AU - O. Genevois AU - E. Plaisier AU - J.A. Sahel PY - 2011 DA - 2011/11/29 TI - P2.11 IMAGING OF RETINAL ARTERIOLAR WALL IN VIVO IN HUMANS JO - Artery Research SP - 155 EP - 155 VL - 5 IS - 4 SN - 1876-4401 UR - https://doi.org/10.1016/j.artres.2011.10.032 DO - 10.1016/j.artres.2011.10.032 ID - Paques2011 ER -