P7.03 MARATHON RUNNERS HAVE INCREASED AORTIC STIFFNESS

DOI

10.1016/j.artres.2009.10.096How to use a DOI?

Abstract

Purpose: It is well known that regular moderate aerobic exercise has a beneficial effect on cardiovascular risk, although the impact of long-term intense aerobic training has not been defined. Aortic stiffness and wave reflections are independent predictors of cardiovascular risk. In this study we assessed the chronic effect of intense endurance training on the elastic properties of the large arteries.

Methods: The study population consisted of 49 healthy (mean age: 37±5yrs), regularly trained (5.8±3.6hours/week for 11.6±9.1 years) marathon runners (mean age: 38±9yrs) and 46 controls matched for classical risk factors. Aortic stiffness was evaluated with carotid-femoral pulse wave velocity (PWV) and wave reflections with augmentation index (AIx) of the aortic pressure waveform.

Results: Marathon runners had significantly higher systolic pressure (aortic and brachial) (113±15 vs. 102±11, P<0.01 and 126±15 vs. 115±12, P<0.01, respectively) compared to controls. Aortic and brachial diastolic pressure- (79±10 vs.72±9, P<0.01 and 78±10 vs.71±9, P<0.01, respectively) and mean pressure (94±12 vs. 86±10, P=0.01) were also increased compared to controls. PWV was increased in athletes compared to controls (6.9±1 vs. 6.3±1, P<0.01), indicating increased aortic stiffness. AIx corrected for heart rate (8.2±12.2 vs. 10.3±9.5, P=NS) did not differ among the two groups. Years of exercise were associated with aortic pulse pressure (r=0.304, P=0.045) and AIx (r=0.388, P=0.009) in athletes.

Conclusions: Marathon runners have increased aortic stiffness, as welll as central and peripheral haemodynamic parameters. These findings could contribute to precisely assess cardiovascular risk in marathon runners focusing on the proper training volumes, frequency and duration.

Open Access

This is an open access article distributed under the CC BY-NC license.

Download article (PDF)
View full text (HTML)

TY  - JOUR
AU  - D. Kardara
AU  - C. Vlachopoulos
AU  - A. Anastasakis
AU  - K. Baou
AU  - D. Terentes-Printzios
AU  - I. Dima
AU  - G. Antoniou
AU  - A. Gravos
AU  - C. Stefanadis
PY  - 2009
DA  - 2009/12/03
TI  - P7.03 MARATHON RUNNERS HAVE INCREASED AORTIC STIFFNESS
JO  - Artery Research
SP  - 183
EP  - 184
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.096
DO  - 10.1016/j.artres.2009.10.096
ID  - Kardara2009
ER  -