P8.06 REFERENCE VALUES FOR ARTERIAL STIFFNESS MEASURED WITH ARTERIOGRAPH

DOI

10.1016/j.artres.2009.10.112How to use a DOI?

Abstract

Elevated aortic pulse wave velocity (aoPWV) is an independent predictor of cardiovascular morbidity and mortality. There are, however, no widely accepted normal or reference values for aoPWV. The aim of this work was to define these values.

Patients and methods: AoPWV was assessed in several patient populations using oscillometric device (TensioMed Arteriograph) by a numerous investigators and data were collected into a large database of 17173 subjects aged 2–92 years. AoPWV was studied in a group of 11024 normotensive individuals without antihypertensive medication which was divided into age decades in order to determine the age-specific reference values for aoPWV.

Results: Mean age was 39,5±20,12 and 43,6±17,82 ys in males and females, respectively (p<0,001). Mean aoPWV differed significantly between genders (7,9±2,3 vs 8,9±2,7; p<0,001). Median aoPWV values in the age subgroups by decades were determined (5.44, 6.08, 6.69, 7.29, 8.38, 9.81, 10.15, 10.41, 11.02m/s from the age under 10 to 80–90, respectively). The 75th and 95th percentiles of the samples were used to determine the upper limit of aoPWV reference values.

Conclusions: The value above 12m/s suggested as a threshold for elevated aoPWV by ESH’07 can be questioned as PWV depends on the method used to calculate the travel distance. Our results derived from a huge healthy general population including wide range of age suggest that aoPWV values are highly dependent on age and gender. Therefore, these results might serve as age and gender specific reference values for aoPWV.

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TY  - JOUR
AU  - B. Benczúr
AU  - R. Böcskei
AU  - M. Illyés
PY  - 2009
DA  - 2009/12/03
TI  - P8.06 REFERENCE VALUES FOR ARTERIAL STIFFNESS MEASURED WITH ARTERIOGRAPH
JO  - Artery Research
SP  - 188
EP  - 188
VL  - 3
IS  - 4
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.10.112
DO  - 10.1016/j.artres.2009.10.112
ID  - Benczúr2009
ER  -