16. IS IT POSSIBLE TO PREDICT CORONARY ARTERY STENOSIS BASED ON CAROTID ARTERY INTIMA MEDIA THICKNESS IN DIABETIC PATIENTS

DOI

10.1016/j.artres.2009.06.030How to use a DOI?

Abstract

Background: Noninvasive measurement of carotid artery intima media thickness (IMT) has been widely used as a surrogate marker of coronary atherosclerosis. However, evidence for the clinical implications of increased carotid IMT in diabetic patients is not well established. The aim of this study was to determine if coronary artery disease (CAD) can be predicted based on carotid IMT, intimal, and medial thickness.

Methods: A total of 569 type 2 diabetic patients (male:female=311:258, mean age=63±9 years) who underwent coronary angiography were divided into two groups. Group 1 was composed of patients with no significant CAD (n=105, male%=37.1%, mean age=61±10 years) on angiography. Group 2 was composed of patients with significant CAD (n=464. male%=58.6%, mean age=64±9 years). Carotid intimal, medial thickness, and IMT were compared between the two groups. Sensitivity and specificity for detecting significant CAD by carotid ultrasound were evaluated.

Results: There were significant differences in the right maximal IMT, mean IMT, and medial thickness for both carotid arteries. However, there were no significant differences in the left maximal IMT and intimal thickness (Table). A right IMT of 1.13mm and a left IMT of 1.19mm had 94% sensitivity and 80% specificity for CAD, respectively. A right medial thickness of 0.99mm and a left medial thickness of 1.03mm had 100% sensitivity and 86% specificity.

Conclusion: Carotid medial thickness and IMT were useful as screening methods for detecting significant CAD in patients with diabetes.

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TY  - JOUR
AU  - Jong-Won Chung
AU  - Ho-Joong Youn
AU  - Yun-Seok Choi
AU  - Hee-Jung Hwang
AU  - Jae-Beom Lee
AU  - Woo-Baek Chung
AU  - Chul-Soo Park
AU  - Yong-Seog Oh
AU  - Wook-Sung Chung
AU  - Jae-Hyung Kim
PY  - 2009
DA  - 2009/10/31
TI  - 16. IS IT POSSIBLE TO PREDICT CORONARY ARTERY STENOSIS BASED ON CAROTID ARTERY INTIMA MEDIA THICKNESS IN DIABETIC PATIENTS
JO  - Artery Research
SP  - 98
EP  - 98
VL  - 3
IS  - 3
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2009.06.030
DO  - 10.1016/j.artres.2009.06.030
ID  - Chung2009
ER  -