Artery Research

Volume 25, Issue 3-4, December 2019, Pages 151 - 155

Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function

Authors
Alinne Nascimento, Duarte Barros, José Oliveira, Joana Carvalho, Lucimere Bohn*
Research Centre in Physical Activity, Health and Leisure (CIAFEL), Faculty of Sports, University of Porto, 91, Rua Dr. Plácido Costa, Porto 4200-450, Portugal
*Corresponding author. Email: lucimerebohn@gmail.com
Corresponding Author
Lucimere Bohn
Received 13 November 2019, Accepted 18 November 2019, Available Online 2 December 2019.
DOI
10.2991/artres.k.191121.001How to use a DOI?
Keywords
Physical fitness; arterial stiffness; cognition; elders; pulse wave velocity
Abstract

Background: To investigate physical fitness as a mediator of the relationship between arterial stiffness and cognitive function in seniors.

Methods: This is a cross-sectional study comprising 155 individuals free from chronic diseases (75.5 ± 6.5 years; 69.7% female). Carotid-femoral pulse wave was assessed through applanation tonometry. Cognitive function was evaluated with Montreal Cognitive Assessment (MoCA). Physical fitness was assessed through handgrip strength and Senior Fitness Test (SFT). A Z-score including individual physical fitness components was computed as a global index of physical fitness. Hayes’s PROCESS macro for Statistical Package for the Social Sciences was used for the simple mediation analysis, using bootstrapped procedures.

Results: After adjustments for sex and age, physical fitness Z-score mediated the relationship between arterial stiffness and cognitive function [Indirect effect = −0.382 (95% CI −0.670 to −0.138)].

Conclusion: Findings suggest that physical fitness, independently of sex and age, is a mediator on the relationship between arterial stiffness and cognitive function in seniors free from chronic diseases.

Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal
Artery Research
Volume-Issue
25 - 3-4
Pages
151 - 155
Publication Date
2019/12/02
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.2991/artres.k.191121.001How to use a DOI?
Copyright
© 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
Open Access
This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

Cite this article

TY  - JOUR
AU  - Alinne Nascimento
AU  - Duarte Barros
AU  - José Oliveira
AU  - Joana Carvalho
AU  - Lucimere Bohn
PY  - 2019
DA  - 2019/12/02
TI  - Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function
JO  - Artery Research
SP  - 151
EP  - 155
VL  - 25
IS  - 3-4
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191121.001
DO  - 10.2991/artres.k.191121.001
ID  - Nascimento2019
ER  -