Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function
- DOI
- 10.2991/artres.k.191121.001How to use a DOI?
- Keywords
- Physical fitness; arterial stiffness; cognition; elders; pulse wave velocity
- Abstract
Background: To investigate physical fitness as a mediator of the relationship between arterial stiffness and cognitive function in seniors.
Methods: This is a cross-sectional study comprising 155 individuals free from chronic diseases (75.5 ± 6.5 years; 69.7% female). Carotid-femoral pulse wave was assessed through applanation tonometry. Cognitive function was evaluated with Montreal Cognitive Assessment (MoCA). Physical fitness was assessed through handgrip strength and Senior Fitness Test (SFT). A Z-score including individual physical fitness components was computed as a global index of physical fitness. Hayes’s PROCESS macro for Statistical Package for the Social Sciences was used for the simple mediation analysis, using bootstrapped procedures.
Results: After adjustments for sex and age, physical fitness Z-score mediated the relationship between arterial stiffness and cognitive function [Indirect effect = −0.382 (95% CI −0.670 to −0.138)].
Conclusion: Findings suggest that physical fitness, independently of sex and age, is a mediator on the relationship between arterial stiffness and cognitive function in seniors free from chronic diseases.
- Copyright
- © 2019 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
- Open Access
- This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).
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TY - JOUR AU - Alinne Nascimento AU - Duarte Barros AU - José Oliveira AU - Joana Carvalho AU - Lucimere Bohn PY - 2019 DA - 2019/12/02 TI - Physical Fitness is a Mediator in the Relationship between Arterial Stiffness and Cognitive Function JO - Artery Research SP - 151 EP - 155 VL - 25 IS - 3-4 SN - 1876-4401 UR - https://doi.org/10.2991/artres.k.191121.001 DO - 10.2991/artres.k.191121.001 ID - Nascimento2019 ER -