P74 Validation of Surface Distance Measurement by MRI for Pulse Wave Velocity in Children

Adrienn Bárczi; Arianna Dégi; Orsolya Cseprekál; Eva Kis; Ádám Szabó; Gábor Rudas; George S Reusz

doi:10.2991/artres.k.191224.105

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Volume 25, Issue Supplement 1, December 2019, Pages S118 - S118

P74 Validation of Surface Distance Measurement by MRI for Pulse Wave Velocity in Children

Authors

Adrienn Bárczi¹^{, *}, Arianna Dégi¹, Orsolya Cseprekál², Eva Kis³, Ádám Szabó⁴, Gábor Rudas⁴, George S Reusz¹

¹1st Department of Pediatrics, Semmelweis University, Budapest, Hungary

²Department of Transplantation and Surgery, Semmelweis Univeristy, Budapest, Hungary

³Gottsegen György Hungarian Institute of Cardiology, Budapest, Hungary

⁴Semmelweis University, MR Research Center, Budapest, Hungary

^*Corresponding author. Email: adriennbarczi@gmail.com

Corresponding Author

Adrienn Bárczi

Available Online 17 February 2020.

DOI: 10.2991/artres.k.191224.105 How to use a DOI?
Abstract: Background: Aortic pulse wave velocity (PWV) is the gold standard measurement for arterial stiffness. Normative values exist for PWV in children using the subtracted method (LSM) for the estimation of the distance, however no imaging validation studies in the growing pediatric population. The formula of 0.8 × surface distance (L0.8) based on MRI validation is only used in adults. Our aim was to compare the different techniques of surface measurement and distances determined by MRI in pediatric subjects.

Methods: 21 patients were included (3.2–17.8 years) in the study. Pulse wave travel distance was assessed by surface tape measurements. Carotid-femoral path length was also measured by MRI. To calculate the reference distance (LREF) for the real aortic path length, centerpoints were placed manually in each slice and a centerline was reconstructed. Bland-Altman plots (BA) were used to assess the difference between the distances measured on surface or intraarterial.

Results: There was a high correlation (r > 0.86, p < 0.001) between surface and MRI distance measurements. According to L0.8 and LREF values the average difference was 35.9 cm and BA plots showed significant difference. The difference between LSM and LREF was 2 cm and in the BA analysis LSM and LREF were in good accordance. There was a proportional error in the BA plots in patients over 13 years.

Conclusion: In our study group the path length assessed by the subtracted method showed excellent correlation with intra-arterial MRI measurements. The small number of cases does not allow to conclude the difference in postpubertal patients, which needs further evaluation.
Open Access: This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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Journal: Artery Research
Volume-Issue: 25 - Supplement 1
Pages: S118 - S118
Publication Date: 2020/02/17
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.2991/artres.k.191224.105 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC 4.0 license (http://creativecommons.org/licenses/by-nc/4.0/).

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ris enw bib

TY  - JOUR
AU  - Adrienn Bárczi
AU  - Arianna Dégi
AU  - Orsolya Cseprekál
AU  - Eva Kis
AU  - Ádám Szabó
AU  - Gábor Rudas
AU  - George S Reusz
PY  - 2020
DA  - 2020/02/17
TI  - P74 Validation of Surface Distance Measurement by MRI for Pulse Wave Velocity in Children
JO  - Artery Research
SP  - S118
EP  - S118
VL  - 25
IS  - Supplement 1
SN  - 1876-4401
UR  - https://doi.org/10.2991/artres.k.191224.105
DO  - 10.2991/artres.k.191224.105
ID  - Bárczi2020
ER  -

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