Artery Research

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Volume 24, Issue C, December 2018, Pages 117 - 117

P131 UTERINE ARTERIES EVALUATION DURING PREGNANCY: MODELING AND COMPUTATIONAL FLUID DYNAMICS CALCULATIONS

Authors
Andreia Serrano1, 2, Vanessa Cunha3, Jorge Teixeira4, Maria Pires5, João O’Neill5, Valentina Vassilenko3
1LIBPhys – Laboratory of Instrumentation, Biomedical Engineering and Radiation Physics, Faculty of Science and Technology, New University of Lisbon, Caparica, Portugal
2NMT, S. A., Madan Park Building, Rua dos Inventores, Caparica, Portugal
3Laboratório de Instrumentação, Engenharia Biomédica e Física da Radiação (LIBPhys-UNL), Departamento de Física, Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa, Monte da Caparica, 2829-516, Caparica, Portugal
4UNIDEMI, Departamento de Engenharia Mecânica e Industrial, Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Campus da Caparica, 2829-516, Caparica, Portugal
5Anatomy Department, Nova Medical School, New University of Lisbon, Lisboa, Portugal
Available Online 4 December 2018.
DOI
10.1016/j.artres.2018.10.184How to use a DOI?
Abstract

Preeclampsia (PE) affects pregnancy, being one of the main causes of prenatal maternal mortality and morbidity (1). Recent studies show that PE is characterized by a significant reduction on maternal cardiac output and increased peripheral resistance. However, studies on the maternal hemodynamic adaptation during PE and the available information about central maternal hemodynamics are scarce. Our purpose is to develop a computational model to obtain relevant hemodynamic parameters of the maternal circulation, formed by the common iliac (CI), the internal (II) and the external iliac (EI) and the uterine arteries (UA). Model construction requires many approximations and generalizations to optimize numerical calculation of hemodynamic parameters by Computational Fluid Dynamics (CFD), however this is the best representation of maternal circulatory system. Four different models were created to simulate non-pregnant women and 21, 30 and 36 weeks of pregnancy (2). Numerical simulations performed by ANSYS®-Fluent software correlate blood flow, velocity and arterial pressure, with the variation of uterine morphological data. Calculated flow values on CI and UA to different geometries represent the evolution of arterial system during pregnancy. As the UA suffers higher geometrical transformations during pregnancy, there are a greater increase on blood velocity; blood velocity on the EI increases, remaining almost constant in the CI arteries.The growth on blood flow due to pregnancy development is associated to an augmentation on the arteries’ diameter, which allows the maintenance of blood pressure on UA.This model is suitable to compare wall shear, velocity or flow values associated to PE, measured in clinical context.

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Journal
Artery Research
Volume-Issue
24 - C
Pages
117 - 117
Publication Date
2018/12/04
ISSN (Online)
1876-4401
ISSN (Print)
1872-9312
DOI
10.1016/j.artres.2018.10.184How to use a DOI?
Open Access
This is an open access article distributed under the CC BY-NC license.

Cite this article

risenwbib
TY  - JOUR
AU  - Andreia Serrano
AU  - Vanessa Cunha
AU  - Jorge Teixeira
AU  - Maria Pires
AU  - João O’Neill
AU  - Valentina Vassilenko
PY  - 2018
DA  - 2018/12/04
TI  - P131 UTERINE ARTERIES EVALUATION DURING PREGNANCY: MODELING AND COMPUTATIONAL FLUID DYNAMICS CALCULATIONS
JO  - Artery Research
SP  - 117
EP  - 117
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.184
DO  - 10.1016/j.artres.2018.10.184
ID  - Serrano2018
ER  -