P130 COMPARISON BETWEEN PWV MEASURED FROM CUTANEOUS LENGTH BY SPHYGMOCOR AND BY MRI LENGTH TRACED ALONG THE WHOLE AORTA

DOI

10.1016/j.artres.2018.10.183How to use a DOI?

Abstract

Background: Accuracy of non-invasive PWV as m/sec is impeded by crude surface estimates of aortic length. We compared PWV measured using the Sphygmocor via surface length measurements with PWV measured using MRI with distance traced more precisely along the whole imaged aortic length.

Methods: Magnetic resonance imaging (MRI) was performed in 74 asymptomatic women aged between 51–80 years of age. Carotid-femoral PWV was measured using Sphygmocor. The path distance between the carotid and femoral sites was estimated from the distance between the sternal notch and femoral artery at the point of applanation. Phase-contrast MRI was performed at the level of the aortic arch and distal to the aortic bifurcation to obtain aortic flow. Aortic distance was measured by tracing the centre of the aorta from a black-blood MRI sequence.

Results: Mean (±SD) carotid-femoral transit time (TT) measured by Sphygmocor (58 ± 11 ms) was 2.9 [95% confidence interval (CI) 0.85–5.0]ms higher than aortic TT measured by MRI (54 ± 12 ms). The carotid-femoral surface distance estimate (552 ± 33 mm) was 15 [142–162]mm higher than the aortic length estimate (399 ± 32 mm). Corresponding PWVs estimated with Sphygmocor and MRI were 9.87 ± 2.1 and 7.63 ± 1.9 (P < 0.001) m/s, respectively. PWV differences between Sphygmocor and MRI decreased to 0.50 (0.13–0.86)m/s when Sphygmocor PWV was calculated using the MRI path length.

Conclusion: In these older women, the PWV difference between Sphygmocor and MRI is reduced when MRI length estimates are used. The difference between PWV measured by Sphygmocor and MRI is in part due to the accuracy of distance measurements.

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TY  - JOUR
AU  - Marina Cecelja
PY  - 2018
DA  - 2018/12/04
TI  - P130 COMPARISON BETWEEN PWV MEASURED FROM CUTANEOUS LENGTH BY SPHYGMOCOR AND BY MRI LENGTH TRACED ALONG THE WHOLE AORTA
JO  - Artery Research
SP  - 117
EP  - 117
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.183
DO  - 10.1016/j.artres.2018.10.183
ID  - Cecelja2018
ER  -