P121 ASSOCIATION OF CARDIORESPIRATORY FITNESS WITH ARTERIAL STIFFNESS AND PERIPHERAL AND CENTRAL BLOOD PRESSURE IN RESISTANT HYPERTENSION PATIENTS

Catarina Garcia; Susana Lopes; Susana Bertoquini; Verónica Ribau; Cátia Leitão; Daniela Figueiredo; Ilda P Ribeiro; Joana Barbosa de Melo; João L Viana; José Mesquita-Bastos; Jorge Polónia; Fernando Ribeiro; Alberto J Alves

doi:10.1016/j.artres.2018.10.174

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Volume 24, Issue C, December 2018, Pages 114 - 114

P121 ASSOCIATION OF CARDIORESPIRATORY FITNESS WITH ARTERIAL STIFFNESS AND PERIPHERAL AND CENTRAL BLOOD PRESSURE IN RESISTANT HYPERTENSION PATIENTS

Authors

Catarina Garcia¹, Susana Lopes¹, Susana Bertoquini², Verónica Ribau³, Cátia Leitão⁴, Daniela Figueiredo⁵, Ilda P Ribeiro⁶, Joana Barbosa de Melo⁶, João L Viana⁷, José Mesquita-Bastos⁵, Jorge Polónia², Fernando Ribeiro¹, Alberto J Alves⁸

¹School of Health Sciences and Institute of Biomedicine - iBiMED, University of Aveiro, Aveiro, Portugal

²Faculty of Medicine, University of Porto, & Hypertension Unit, ULS, Matosinhos, Portugal

³Department, Hospital Infante D. Pedro, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal

⁴Departmente of Physics & I3N and Instituto de Telecomunicações, University of Aveiro, Portugal

⁵School of Health Sciences and CINTESIS@UA, University of Aveiro, Portugal

⁶Center of Investigation on Environment Genetics and Oncobiology (CIMAGO), Faculty of Medicine, University of Coimbra, and Center for Neuroscience and Cell Biology and Institute for Biomedical Imaging and Life Sciences (CNC.IBILI), Coimbra, Portugal

⁷Sports Sciences, Health Sciences and Human Development – CIDESD, University Institute of Maia, Portugal

⁸Sports Sciences, Health Sciences and Human Development – CIDESD, University Institute of Maia, Portugal

Available Online 4 December 2018.

DOI: 10.1016/j.artres.2018.10.174 How to use a DOI?
Abstract: Background: The relationship between arterial stiffness, blood pressure (BP) and cardiorespiratory fitness (CRF) has been studied in healthy populations and cardiovascular patients, since all of which proved to be independent predictors of all-cause mortality. We aimed to investigate the association of CRF with arterial stiffness and peripheral and central hemodynamics, in patients with resistant hypertension (RT).

Methods: In this cross-sectional study, 30 patients (13 men, 17 women; age, 57.7 ± 8.1 years; weight, 79.2 ± 11.6 kg; body mass index, 29.7 ± 4.0 kg/m²) with resistant hypertension were recruited in the Hospital Infante D. Pedro (Aveiro) and Hospital Pedro Hispano (Matosinhos). Outcome measures included CRF (VO2peak), peripheral and central BP, and carotid-femoral pulse wave velocity (cf-PWV). Correlation analysis was conducted to assess the association between variables.

Results: A significant negative correlation was found between VO2peak (33.7 ± 6.2 mLO₂/kg/min) and central (141.0±21.3 mmHg; r = −0.395, p = 0.031) and peripheral systolic BP (148.4 ± 21.3 mmHg; r = −0.363, p = 0.049). VO2peak was also correlated with pulse pressure (PP) amplification ratio (1.2 ± 0.1 mmHg; r = 0.361, p = 0.050). The association with central systolic BP (r = −0.403, p = 0.035) and PP amplification ratio (r = 0.408, p = 0.033) remained significant after adjusted for age. VO2peak showed no correlation with PWV (9.4 ± 2.9 m/s; r = −0.075, p = 0.694) and peripheral (88.1 ± 12.2 mmHg; r = −0.138 p = 0.467) and central diastolic BP (88.5 ± 12.7 mmHg; r = −0.133, p = 0.483).

Conclusion: This study confirms the inverse relationship between CRF and central systolic BP and PP amplification ratio in RH patients, regardless of age.
Open Access: This is an open access article distributed under the CC BY-NC license.

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Journal: Artery Research
Volume-Issue: 24 - C
Pages: 114 - 114
Publication Date: 2018/12/04
ISSN (Online): 1876-4401
ISSN (Print): 1872-9312
DOI: 10.1016/j.artres.2018.10.174 How to use a DOI?
Open Access: This is an open access article distributed under the CC BY-NC license.

Cite this article

ris enw bib

TY  - JOUR
AU  - Catarina Garcia
AU  - Susana Lopes
AU  - Susana Bertoquini
AU  - Verónica Ribau
AU  - Cátia Leitão
AU  - Daniela Figueiredo
AU  - Ilda P Ribeiro
AU  - Joana Barbosa de Melo
AU  - João L Viana
AU  - José Mesquita-Bastos
AU  - Jorge Polónia
AU  - Fernando Ribeiro
AU  - Alberto J Alves
PY  - 2018
DA  - 2018/12/04
TI  - P121 ASSOCIATION OF CARDIORESPIRATORY FITNESS WITH ARTERIAL STIFFNESS AND PERIPHERAL AND CENTRAL BLOOD PRESSURE IN RESISTANT HYPERTENSION PATIENTS
JO  - Artery Research
SP  - 114
EP  - 114
VL  - 24
IS  - C
SN  - 1876-4401
UR  - https://doi.org/10.1016/j.artres.2018.10.174
DO  - 10.1016/j.artres.2018.10.174
ID  - Garcia2018
ER  -

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