Burden of laboratory-confirmed Campylobacter infections in Guatemala 2008–2012: Results from a facility-based surveillance system
- DOI
- 10.1016/j.jegh.2013.10.001How to use a DOI?
- Keywords
- Campylobacter; Guatemala; Epidemiology; Antimicrobial resistance
- Abstract
Introduction: Campylobacteriosis is one of the leading causes of gastroenteritis worldwide. This study describes the epidemiology of laboratory-confirmed Campylobacter diarrheal infections in two facility-based surveillance sites in Guatemala.
Methods: Clinical, epidemiologic, and laboratory data were collected on patients presenting with acute diarrhea from select healthcare facilities in the departments of Santa Rosa and Quetzaltenango, Guatemala, from January 2008 through August 2012. Stool specimens were cultured for Campylobacter and antimicrobial susceptibility testing was performed on a subset of isolates. Multidrug resistance (MDR) was defined as resistance to ⩾3 antimicrobial classes.
Results: Campylobacter was isolated from 306 (6.0%) of 5137 stool specimens collected. For children <5 years of age, annual incidence was as high as 1288.8 per 100,000 children in Santa Rosa and 185.5 per 100,000 children in Quetzaltenango. Among 224 ambulatory care patients with Campylobacter, 169 (75.5%) received metronidazole or trimethoprim-sulfamethoxazole, and 152 (66.7%) received or were prescribed oral rehydration therapy. Antimicrobial susceptibilities were tested in 96 isolates; 57 (59.4%) were resistant to ciprofloxacin and 12 (12.5%) were MDR.
Conclusion: Campylobacter was a major cause of diarrhea in children in two departments in Guatemala; antimicrobial resistance was high, and treatment regimens in the ambulatory setting which included metronidazole and trimethoprim-sulfamethoxazole and lacked oral rehydration were sub-optimal.
- Copyright
- Published by Elsevier Ltd. on behalf of Ministry of Health, Saudi Arabia.
- Open Access
- This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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TY - JOUR AU - Stephen R. Benoit AU - Beatriz Lopez AU - Wences Arvelo AU - Olga Henao AU - Michele B. Parsons AU - Lissette Reyes AU - Juan Carlos Moir AU - Kim Lindblade PY - 2013 DA - 2013/11/12 TI - Burden of laboratory-confirmed Campylobacter infections in Guatemala 2008–2012: Results from a facility-based surveillance system JO - Journal of Epidemiology and Global Health SP - 51 EP - 59 VL - 4 IS - 1 SN - 2210-6014 UR - https://doi.org/10.1016/j.jegh.2013.10.001 DO - 10.1016/j.jegh.2013.10.001 ID - Benoit2013 ER -