The Role of Cystatin C and Albumin in the Differential Diagnosis of Primary Chronic Glomerulonephritis and Hypertension-Induced Renal Injury
- DOI
- 10.2991/assehr.k.200205.025How to use a DOI?
- Keywords
- primary chronic glomerulonephritis, Hypertension-induced renal injury, Cystatin C, Albumin
- Abstract
Background: It was difficult to differentiate diseases in patients of Primary chronic glomerulonephritis (PCG) and Hypertension-induced renal injury (HRI). This study aimed to investigate the role of serum Cystatin C and Albumin in differential diagnosis of PCG and HRI. Materials and Methods: A total of 150 patients (79 PCG and 71 HRI) considering for our clinic between October 2017 and August 2018 were included. Patients were included in the study newly diagnosed by biopsy. Urinary samples and blood samples were collected and measured. The diagnostic roles were investigated using the receiver operator curve curves. Results: There was an increased serum levels of Albumin in patients with PCG compared with that in patients with HRI. Patients with HRI had a significantly increased serum levels of Cystatin C than those with PCG. An Albumin level of 2.295 g/L had an 80.3% sensitivity and a 73.4% specificity, Cystatin C level of 36.200 mg/L had a 79.7% sensitivity and a 93% specificity for differential diagnosis of PCG and HRI. Conclusions: Serum Cystatin C and Albumin level might be used as tool to differentiate PCG from HRI. Further studies are needed to confirm the definite the role of those markers.
- Copyright
- © 2020, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Shen Li AU - Changle Zhang AU - Ke Zhang AU - Jumin Song PY - 2020 DA - 2020/02/13 TI - The Role of Cystatin C and Albumin in the Differential Diagnosis of Primary Chronic Glomerulonephritis and Hypertension-Induced Renal Injury BT - Proceedings of the Third International Conference on Social Science, Public Health and Education (SSPHE 2019) PB - Atlantis Press SP - 112 EP - 115 SN - 2352-5398 UR - https://doi.org/10.2991/assehr.k.200205.025 DO - 10.2991/assehr.k.200205.025 ID - Li2020 ER -