Proceedings of the 4th International Conference on Public Administration, Health and Humanity Development (PAHHD 2024)

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Research and Prospects of Anticoagulant Drugs: A Review

Authors
Zeyu Xiao1, *
1Dongfang College, Beijing University of Chinese Medicine, Cangzhou, Hebei, China
*Corresponding author. Email: 2360857581@qq.com
Corresponding Author
Zeyu Xiao
Available Online 21 October 2024.
DOI
10.2991/978-2-38476-295-8_19How to use a DOI?
Keywords
Thrombin; Coagulation factors; Traditional anticoagulants; New Anticoagulant Drugs
Abstract

Anticoagulants prevent blood clotting by interfering with the body’s physiological clotting process. Anticoagulants are mainly used to prevent the formation of blood clots and to stop the development of clots that have already formed. However, anticoagulants already in clinical use have many drawbacks. Conventional anticoagulants, which usually act on multiple coagulation factor targets, have proven efficacy in the prevention and treatment of thromboembolic disease. However, there are many inconveniences in clinical application. These inconveniences include slow onset of action, narrow therapeutic window and safe dosage range, high variability of the dose-effect relationship between individuals, susceptibility of blood levels to the effects of a variety of foods or medications, genetic and environmental factors affecting absorption and metabolism, and the need for frequent monitoring and dosage adjustments. Therefore, the development of new anticoagulants is imperative. The aim of this paper is to introduce traditional and novel anticoagulants and to provide an outlook on the future development of anticoagulants.

Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 4th International Conference on Public Administration, Health and Humanity Development (PAHHD 2024)
Series
Advances in Social Science, Education and Humanities Research
Publication Date
21 October 2024
ISBN
978-2-38476-295-8
ISSN
2352-5398
DOI
10.2991/978-2-38476-295-8_19How to use a DOI?
Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - Zeyu Xiao
PY  - 2024
DA  - 2024/10/21
TI  - Research and Prospects of Anticoagulant Drugs: A Review
BT  - Proceedings of the 4th International Conference on Public Administration, Health and Humanity Development (PAHHD 2024)
PB  - Atlantis Press
SP  - 157
EP  - 163
SN  - 2352-5398
UR  - https://doi.org/10.2991/978-2-38476-295-8_19
DO  - 10.2991/978-2-38476-295-8_19
ID  - Xiao2024
ER  -