Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)

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Relationship of Nodule Type and Size with Thyroid Malignancy

Authors
Anton Sony Wibowo1, 3, *, Camelia Herdini1, 2, Bambang Udji Djoko Rianto1, 2
1Otorhinolaringology-Head and Neck Surgery Department School of Medicine Universitas Gadjah Mada, Indonesia
2RSUP Dr. Sardjito Yogyakarta, Indonesia
3Universitas Gadjah Mada, Academic Hospital Yogyakarta, Indonesia
*Corresponding author. Email: antonsonywibowo@ugm.ac.id
Corresponding Author
Anton Sony Wibowo
Available Online 21 February 2022.
DOI
10.2991/ahsr.k.220206.020How to use a DOI?
Keywords
thyroid nodule; multinodular; uninodular; thyroid nodule size; thyroid malignance
Abstract

Thyroid carcinoma was the common head-neck malignancy. Clinical examination was essential at the initial suspicion of thyroid malignancy. Thyroid size and nodularity were the first things in a physical examination of the thyroid. This study aimed to determine the relationship between the type and size of thyroid nodules and their malignancy. This research was a case-control study. The case group was malignant thyroid nodules, while the control group was benign thyroid nodules. The study subjects were patients with thyroid nodules who underwent thyroidectomy surgery at RSUP. Dr. Sardjito Yogyakarta, between 2016-2018. The type of nodules was determined by computerized tomography (CT) scan. The size of the nodules was determined by a CT scan. The difference of nodularity was analyzed within each group and between study groups. The subject consisted of 50 patients who underwent thyroidectomy, each group consisted of 25 patients. There was no significant difference in nodule type (multinodular and unimodular) between benign and malignant thyroid nodul with p value 0.079 (p< 0.05, 95% CI). There was no significant difference in nodule size between benign and malignant thyroid nodul with p value = 0.148 (p> 0.05, 95% CI) and Odds Ratio (OR)= 0.67 (95% CI 0.19 -2.32). Multivariate analysis was performed. The dependent variable was nodule malignancy. The independent variables were age, sex, TSH level, free-T4 level, nodule type and nodule size. The results of the logistic regression analysis showed statistically significant results only at TSH levels with p value = 0.005. The conclusion of this study was that the type of nodule (multinodular and uninodular), and nodule size were not related to the thyroid malignancy statistically.

Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

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Volume Title
Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
Series
Advances in Health Sciences Research
Publication Date
21 February 2022
ISBN
978-94-6239-540-4
ISSN
2468-5739
DOI
10.2991/ahsr.k.220206.020How to use a DOI?
Copyright
© 2022 The Authors. Published by Atlantis Press International B.V.
Open Access
This is an open access article under the CC BY-NC license.

Cite this article

risenwbib
TY  - CONF
AU  - Anton Sony Wibowo
AU  - Camelia Herdini
AU  - Bambang Udji Djoko Rianto
PY  - 2022
DA  - 2022/02/21
TI  - Relationship of Nodule Type and Size with Thyroid Malignancy
BT  - Proceedings of the 2nd Global Health and Innovation in conjunction with 6th ORL Head and Neck Oncology Conference (ORLHN 2021)
PB  - Atlantis Press
SP  - 97
EP  - 101
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220206.020
DO  - 10.2991/ahsr.k.220206.020
ID  - Wibowo2022
ER  -