Effects of Preoperative Enteral Nutrition Support on Postoperative Nutritional Status and Immune Function of Colorectal Cancer Patients
- DOI
- 10.2991/msetasse-16.2016.273How to use a DOI?
- Keywords
- Enteral Nutrition, Colorectal Cancer, Preoperation, Immunity
- Abstract
We performed a prospective randomized clinical trial to evaluate the effects of preoperative one week enteral nutrition (EN) support on the postoperative nutritional status, immune function and inflammatory response of colorectal cancer patients. Materials and Methods: 96 patients undergoing colorectal surgery were randomly divided into preoperative one week EN group (trial group, n=48) and preoperative normal food group (control group, n=48). The EN group was continuously treated with EN support for 7 days according to the treatment protocols before operation. The control group was given normal food. All the patients were checked for their body weight, upper arm circumference, white blood cell count (WBC), albumin (ALB), prealbumin (PA), C-reactive protein (CRP), humoral immunity (IgA, IgG), T cell subsets (CD4, CD8 and CD4/CD8), interleukin-6 (IL-6), tumor necrosis factor- (TNF- ) on the preoperative and the postoperative 1st and 7th day, respectively. Results: PA and IgG levels of the experimental group were higher than those of the control group on the postoperative 7th day, whereas IL-6 level of the experimental group was lower than that of the control group. Conclusion: Preoperative one week EN support for colorectal cancer patients will improve the postoperative nutritional status and immune function, alleviate inflammatory response of colorectal cancer patients.
- Copyright
- © 2016, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Dayong Ding AU - Dan Wang AU - Zhenbo Shu PY - 2016/11 DA - 2016/11 TI - Effects of Preoperative Enteral Nutrition Support on Postoperative Nutritional Status and Immune Function of Colorectal Cancer Patients BT - Proceedings of the 2016 4th International Conference on Management Science, Education Technology, Arts, Social Science and Economics (msetasse-16) PB - Atlantis Press SP - 1282 EP - 1287 SN - 2352-5398 UR - https://doi.org/10.2991/msetasse-16.2016.273 DO - 10.2991/msetasse-16.2016.273 ID - Ding2016/11 ER -