Investigation of HP- -CD Inclusion Compound Preparation Process for Pulsatilla Chinensis (Bunge) Regel Total Saponins

DOI

10.2991/mebe-15.2015.179How to use a DOI?

Keywords

Pulsatilla chinensis (Bunge) Regel total saponins; HP- -CD; inclusion compound.

Abstract

This paper used parallel test of single factor to investigate feed ratio of inclusion compound, drying method, the volatilization temperature of ethanol for Pulsatilla Chinensis (Bunge) Regel total saponins-HP- -CD inclusion compound. The results showed that the best preparation process of inclusion compound was as following: the feed ratio of Pulsatilla total saponin extract and HP- -CD was 1:1; After the Pulsatilla total saponins extract with ethanol solution was dropwise added to the HP- -CD aqueous solution, the mixed solution was continuously stirred for 6h at 60 and was freeze-dried for 12h. The preparation process for Pulsatilla Chinensis (Bunge) Regel total saponins-HP- -CD inclusion compound was simple and it is helpful to improve the drug dissolution.

Copyright

© 2015, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Zhenhua Chen
AU  - Suzhen Liu
AU  - Yongmei Guan
AU  - Ni Zhang
AU  - Ming Yang
AU  - Hongning Liu
PY  - 2015/04
DA  - 2015/04
TI  - Investigation of HP- -CD Inclusion Compound Preparation Process for Pulsatilla Chinensis (Bunge) Regel Total Saponins
BT  - Proceedings of the 2015 International Conference on Materials, Environmental and Biological Engineering
PB  - Atlantis Press
SP  - 804
EP  - 808
SN  - 2352-5401
UR  - https://doi.org/10.2991/mebe-15.2015.179
DO  - 10.2991/mebe-15.2015.179
ID  - Chen2015/04
ER  -