Computer-Assisted Target Control Infusion System for Elderly Patients during Endoscopic Retrograde Cholangiopancreateography

DOI

10.2991/mcae-16.2016.9How to use a DOI?

Keywords

computer-assisted pump; target control infusion; endoscopic retrograde cholangiopancreateography

Abstract

Objectives: The aim of this study was to investigate the safety and efficacy of propofol sedation with a computer-assisted target-controlled infusionsystem in elderly patients during endoscopic retrograde cholangiopancreateography (ERCP). Methods: Included were 150 consecutive EPCP procedures elderly patients under propofol sedation with a TCI system. Patients were divided into 3 groups: group A, age 50-70 years (n=50); group B, age71-80 years (n=50);group C, age >80 years (n=50). We compared the propofol dose and adverse events (hypotension and hypoxemia) during ERCP. Results: Older patients required a lower target concentration of propofol with higher age period: Median target concentration are respectively 2.6?g/mL,2.1?g/mL and 1.6?g/mL in the three groups. Hypotension tended to occur in the younger group, and hypoxemia occurred at a significantly higher rate in the older groups, although the number of cases was small. Low preoperative systolic blood pressure (<80 mm Hg) was associated with hypotension and abnormal pulmonary function was associated with hypoxemia in groups B and C. Conclusions: Elderly patients required lower doses of propofol with computer-assisted TCI system than younger patients. Attention to hypoxemia is necessary in elderly patients, particularly patients with abnormal pulmonary function.

Copyright

© 2016, the Authors. Published by Atlantis Press.

Open Access

This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).

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TY  - CONF
AU  - Kai Li
AU  - Bin Zhang
AU  - Zhihua Zhu
AU  - Jingpeng Jin
AU  - Yang Liu
PY  - 2016/07
DA  - 2016/07
TI  - Computer-Assisted Target Control Infusion System for Elderly Patients during Endoscopic Retrograde Cholangiopancreateography
BT  - Proceedings of the 2016 International Conference on Mechatronics, Control and Automation Engineering
PB  - Atlantis Press
SP  - 34
EP  - 37
SN  - 2352-5401
UR  - https://doi.org/10.2991/mcae-16.2016.9
DO  - 10.2991/mcae-16.2016.9
ID  - Li2016/07
ER  -