rs841853 of SLC2A1 Gene Polymorphism and Dyslipidemia Among Javanese Type 2 Diabetes Mellitus Patients
- DOI
- 10.2991/978-94-6463-467-9_16How to use a DOI?
- Keywords
- Polymorphism; SLC2A1 Gene; Dyslipidemia; Type 2 Diabetes Mellitus; Javanese
- Abstract
Type 2 Diabetes Mellitus (T2DM) is a chronic disease indicated by blood sugar level disorder and also influenced by genetic and environmental factors. Many diabetes patients experience dyslipidemia, which is known as diabetic dyslipidemia. In the latest research, SLC2A1 gene polymorphism is strongly related to T2DM. This research aimed to investigate the involvement of rs841853 of SLC2A1 gene polymorphism in Javanese diabetes patients with dyslipidemia.This cross-sectional study involved 107 T2DM patients as the sample to verify polymorphism. The occurrence of polymorphism was done using the PCR-RFLP method. The mean of the laboratory characteristic among groups was tested using an independent t-test with a significance of p < 0.05. In both groups, G allele (wild type) and GG genotype were mostly found. There was no difference in allele frequency (p = 0.185) and genotype frequency (p = 0.238). The differences of laboratory characteristic between the GG genotype and TG + TT genotype, either in dyslipidemia or non-dyslipidemia, showed no significance (p > 0.05). Rs841853 of SLC2A1 gene polymorphism was not a significant risk factor for dyslipidemia in Javanese T2DM patients.
- Copyright
- © 2024 The Author(s)
- Open Access
- Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
Cite this article
TY - CONF AU - Yanuarita Tursinawati AU - Ari Yuniastuti PY - 2024 DA - 2024/07/22 TI - rs841853 of SLC2A1 Gene Polymorphism and Dyslipidemia Among Javanese Type 2 Diabetes Mellitus Patients BT - Proceedings of the 2nd Lawang Sewu International Symposium on Health Sciences: Nursing (LSISHS-N 2023) PB - Atlantis Press SP - 174 EP - 180 SN - 2468-5739 UR - https://doi.org/10.2991/978-94-6463-467-9_16 DO - 10.2991/978-94-6463-467-9_16 ID - Tursinawati2024 ER -