The Effectiveness of Galenic Cream of Seromucoid of Snail and Chitosan for Chronic Wound Treatment
- DOI
- 10.2991/978-94-6463-132-6_18How to use a DOI?
- Keywords
- Snail Seromucoid; Chitosan; Galenic; Cream; Chronic Wound
- Abstract
Background: A wound is a form of tissue damage to the skin caused by physical, chemical, and physiological conditions. Treatment of chronic wounds takes a relatively long time so a wound care process or wound management using traditional or modern medical therapy is needed. The development of material-based galenic formulations containing bioactive compounds which can be used for wound care management.
Aim: This research was to test and analyze the effectiveness galenic cream preparations of snail seromucoid and chitosan for wound care in vitro.
Methods: The method was based on the experimental design with the research stages covering bioformulation of galenic cream preparations of snail seromucoid and chitosan as well as testing the quality of galenic preparations physically, chemically, and microbiologically. Analysis of observational data was statistically tested using the One Way Anova.
Results: Bioformulation of seromucoid galenic cream 2.5% and chitosan 2.5% and their combination ratio (1:1), (1:2); (2:1) according to the requirements of BPOM No. 32 of 2019, it eligible the requirements for the quality test of cream preparations in a physicochemical manner including pH, antioxidant activity, dispersion, and adhesion and microbiologically includes Total Plate Number, Yeast Mold Number, and no microbial pathogens Staphylococcus aureus, Pseudomonas aeruginosa, Candida albicans.
Conclusion: Preparation of seromucoid cream and chitosan and their combination ratio (1:1), (1:2); (2:1) can be formulated into galenic cream preparations that can be applied for the treatment of chronic wounds.
- Copyright
- © 2023 The Author(s)
- Open Access
- Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.
Cite this article
TY - CONF AU - Agnes Sri Harti AU - Rahajeng Putriningrum AU - Joko Santoso AU - Sutiyo Dani Saputro AU - Saelan Saelan AU - Yusup Subagio Sutanto PY - 2023 DA - 2023/04/19 TI - The Effectiveness of Galenic Cream of Seromucoid of Snail and Chitosan for Chronic Wound Treatment BT - Proceedings of the 1st Lawang Sewu International Symposium 2022 on Health Sciences (LSISHS 2022) PB - Atlantis Press SP - 146 EP - 157 SN - 2468-5739 UR - https://doi.org/10.2991/978-94-6463-132-6_18 DO - 10.2991/978-94-6463-132-6_18 ID - Harti2023 ER -