The Circulating Level of IL-1β in Patients with Age-related Macular Degeneration (AMD) in Yogyakarta: Characteristics to Disease Activity
- DOI
- 10.2991/absr.k.210621.073How to use a DOI?
- Keywords
- Age-related macular degeneration, inflammation, inflammatory cytokines
- Abstract
Age-related Macular Degeneration (AMD) is leading factors for blindness and impaired visual acuity in developed countries. It is importance to study the dynamic of cytokines concentration during the exudative event of AMD to contribute in the future drugs inventions. This research aims to investigate the IL-1β profiles in plasma of exudative AMD patients. In this cross-sectional study, blood plasma samples from 17 AMD patients and 23 age-matched were collected. Samples were examined for IL-1β inflammatory cytokines using a commercially available ELISA. Acquired data were log transformed to normalize the outlier prior student T-test (SPSS software). Based on recent research, there is a statistically difference of IL-1β among AMD patients and control. IL-1 β concentration were higher at control. Detection of high level of inflammatory cytokines supports a role for inflammation in AMD pathogenesis.
- Copyright
- © 2021, the Authors. Published by Atlantis Press.
- Open Access
- This is an open access article distributed under the CC BY-NC license (http://creativecommons.org/licenses/by-nc/4.0/).
Cite this article
TY - CONF AU - Supanji AU - Ayudha Bahana Ilham Perdamaian AU - Anindita Dianratri AU - Muhammad Eko Prayogo AU - Muhammad Bayu Sasongko AU - Firman Setya Wardhana AU - Tri Wahyu Widayanti AU - Angela Nurini Agni AU - Chio Oka PY - 2021 DA - 2021/06/23 TI - The Circulating Level of IL-1β in Patients with Age-related Macular Degeneration (AMD) in Yogyakarta: Characteristics to Disease Activity BT - Proceedings of the 3rd KOBI Congress, International and National Conferences (KOBICINC 2020) PB - Atlantis Press SP - 434 EP - 436 SN - 2468-5747 UR - https://doi.org/10.2991/absr.k.210621.073 DO - 10.2991/absr.k.210621.073 ID - 2021 ER -