Proceedings of the 4th International Conference on Key Enabling Technologies (KEYTECH 2024)

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Biodegradability Assessment of 3D Printed Polycaprolactone (PCL) for Coronary Stent Applications

Authors
K. Y. Ng1, *, N. Muhammad1, 2, S. N. F. Mohd Noor3, M. S. Saleh1, M. F. Ghazli1, 2, T. Jamil4, N. A. Muhammad5, V. K. Bupesh Raja6
1Faculty of Mechanical Engineering Technology, Universiti Malaysia Perlis, 02600, Arau, Perlis, Malaysia
2Geopolymer and Green Technology, Centre of Excellence Geopolymer and Green Technology, Universiti Malaysia Perlis, 02600, Arau, Perlis, Malaysia
3Biomaterial Unit (CRL 5), Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200, Kepala Batas, Pulau Pinang, Malaysia
4Department of Mechanical Engineering, NED University of Engineering and Technology, Karachi, Pakistan
5School of Mechanical Engineering, Universiti Sains Malaysia, Engineering Campus, 14300, Nibong Tebal, Pulau Pinang, Malaysia
6Department of Automobile Engineering, School of Mechanical Engineering, Sathyabama Institute of Science and Technology, Chennai, India
*Corresponding author. Email: kuangyee0706@gmail.com
Corresponding Author
K. Y. Ng
Available Online 24 December 2024.
DOI
10.2991/978-94-6463-602-4_18How to use a DOI?
Keywords
Coronary artery stents; bioresorbable stents; polycaprolactone (PCL); 3D printing; degradation rate
Abstract

Coronary artery stents, such as bare metal stents and drug-eluting stents, have limitations due to their permanent nature, potentially leading to late stent failure. Bioresorbable stents (BRS), made from materials like polycaprolactone (PCL), offer a solution by degrading completely over time. This study investigates how 3D printing parameters affect the degradation rate of PCL stents. Samples were immersed in simulated body fluid (SBF) for 33 days, and degradation was measured by stent weight and dimensions. The results show significant weight loss and varying degradation rates depending on nozzle temperature (TN), flow rate percentage (PFR), and printing speed (SP). These findings highlight the impact of 3D printing parameters on PCL stent degradation, providing valuable insights for optimizing BRS fabrication for coronary applications.

Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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Volume Title
Proceedings of the 4th International Conference on Key Enabling Technologies (KEYTECH 2024)
Series
Atlantis Highlights in Engineering
Publication Date
24 December 2024
ISBN
978-94-6463-602-4
ISSN
2589-4943
DOI
10.2991/978-94-6463-602-4_18How to use a DOI?
Copyright
© 2024 The Author(s)
Open Access
Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

Cite this article

risenwbib
TY  - CONF
AU  - K. Y. Ng
AU  - N. Muhammad
AU  - S. N. F. Mohd Noor
AU  - M. S. Saleh
AU  - M. F. Ghazli
AU  - T. Jamil
AU  - N. A. Muhammad
AU  - V. K. Bupesh Raja
PY  - 2024
DA  - 2024/12/24
TI  - Biodegradability Assessment of 3D Printed Polycaprolactone (PCL) for Coronary Stent Applications
BT  - Proceedings of the 4th International Conference on Key Enabling Technologies (KEYTECH 2024)
PB  - Atlantis Press
SP  - 124
EP  - 131
SN  - 2589-4943
UR  - https://doi.org/10.2991/978-94-6463-602-4_18
DO  - 10.2991/978-94-6463-602-4_18
ID  - Ng2024
ER  -