Effect of Purple Passion Fruit Juice on Total Cholesterol of Atherogenic Wistar Rat

DOI

10.2991/ahsr.k.220108.024How to use a DOI?

Keywords

purple passion fruit juice; total cholesterol; atherogenic diet; randomized control trial

Abstract

Dyslipidemia is one of the main factor causing atherosclerosis. Dyslipidemia is lipoprotein metabolism disorder which is marked by an increasing of total cholesterol in blood serum. One of the nutrient that can be used to reducing cholesterol synthesis in hepar and inhibit lipid peroxidation is betacaroten that found in purple passion fruit. It contain 1070 µg betacaroten also the other antioksidan such as Vitamin A, Vitamin C, flavonoid and fiber. We conduct experimental study to find out the effect of purple passion fruit juice to total cholesterol in atherogenic wistar rat. We used 30 wistar male rat and randomly divided into 5 groups which received different treatment (normal diet; atherogenic diet; atherogenic diet + 2,3 ml/kg purple passion fruit juice; atherogenic diet + 3,3 ml/kg purple passion fruit juice; atherogenic diet + 4,2 ml/kg purple passion fruit juice with gavage treatment) for 60 days. ANOVA was perform to find out the cholesterol total different in each group. This study show that there was no significant different in total cholesterol wistar male rat (p= 0.057), but compare to group which was not given purple passion fruit juice, it show that there was a trend in reducing total cholesterol as we increased amount purple passion fruit given to wistar male rat. It need further investigation about effective dosage of purple passion fruit juice to reducing total cholesterol serum of rats.

Copyright

© 2022 The Authors. Published by Atlantis Press International B.V.

Open Access

This is an open access article under the CC BY-NC license.

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TY  - CONF
AU  - Farah Paramita
AU  - Hiya Alfi Rahmah
PY  - 2022
DA  - 2022/01/25
TI  - Effect of Purple Passion Fruit Juice on Total Cholesterol of Atherogenic Wistar Rat
BT  - Proceedings of the 3rd International Scientific Meeting on Public Health and Sports (ISMOPHS 2021)
PB  - Atlantis Press
SP  - 137
EP  - 141
SN  - 2468-5739
UR  - https://doi.org/10.2991/ahsr.k.220108.024
DO  - 10.2991/ahsr.k.220108.024
ID  - Paramita2022
ER  -