Hair Tonic Formulation Containing Ethyl Acetate Fraction of Sweet Potato (Ipomoea batatas (L.) Lamk) Leaves and In Vitro Anti-Dandruff Activity Test against Malassezia Furfur

DOI

10.2991/978-94-6463-392-4_22How to use a DOI?

Keywords

Antifungal; Ethyl Acetate Fraction; Hair Tonic; Malassezia furfur; Purple Sweet Potato Leaves

Abstract

Dandruff is a condition where flaking of the skin occurs excessively on the scalp. The primary cause of dandruff is due to the development of Malassezia furfur fungus above normal level. One way to treat dandruff is to reduce the population of Malassezia furfur by using herbs that have antifungal activity. This study aimed to prepare a hair tonic containing ethyl acetate fraction of sweet potato leaves and to test antidandruff activity in vitro against Malassezia furfur. Materials and methods: ethyl acetate fraction of 3% is made hair tonic with the addition of excipient ethanol 96% (5-15%), Propylene glycol (10-30%), tween 80 (1-5%), DMDM Hydantoin, deionized water. Hair tonic was optimized with the d-optimal mixture design method using Design Expert® 10.0.4.0 on physicochemical properties (pH, viscosity, density) and obtained an optimal formula with the use of 96% ethanol of 13.4%, propylene glycol 13.7%, and tween 80 2.9% with a desirability value of 0.881. The optimal formula was tested for antifungal activity against Malassezia furfur using the well-diffusion agar method with PDA-olive oil medium and incubated at 35℃ for 3 days. Results showed that hair tonic had strong antifungal activity equivalent to ketoconazole 2%. Conclusion: The ethyl acetate fraction of sweet potato leaves can be formulated into a hair tonic and has strong antidandruff activity.

Copyright

© 2024 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Fery Indradewi Armadany
AU  - Resmi Mustarichie
AU  - Iyan Sopyan
AU  - Ruslin Ruslin
PY  - 2024
DA  - 2024/04/22
TI  - Hair Tonic Formulation Containing Ethyl Acetate Fraction of Sweet Potato (Ipomoea batatas (L.) Lamk) Leaves and In Vitro Anti-Dandruff Activity Test against Malassezia Furfur
BT  - Proceedings of the 1st International Conference Medical and Health Science Halu Oleo (IMHO 2023)
PB  - Atlantis Press
SP  - 189
EP  - 201
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-392-4_22
DO  - 10.2991/978-94-6463-392-4_22
ID  - Armadany2024
ER  -