The Assessment of the Diagnostic Value of the Heart-Type Fatty Acid-Binding Protein (hFABP) in the Patients Suffering from Chest Pain and Suspected with Acute Coronary Syndrome

DOI

10.2991/978-94-6463-392-4_24How to use a DOI?

Keywords

Acute Myocardial Infarction; hFABP; Troponin T

Abstract

This research aimed to assess the diagnostic value of hFABP in diagnosing the AMI in patients with the chest pain onset ≤6 hours. This diagnostic study was performed on 39 patients with the chest pain onset ≤6 hours in the Emergency Room of Dr Wahidin Sudirohusodo hospital, Makassar from February 2015 through March 2015. The patients were divided into two groups: the AMI group and the Non-AMI group based on the WHO criteria within 12 hours after admission. Then, their diagnostic values, such as the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of the hFABP and troponin T were calculated and compared. The research results revealed that the sensitivity, negative predictive value, and accuracy of the hFABP were higher than the troponin T (87.5% vs 41.6%, 80% vs 51.7%, and 84.6% vs 64.1%, respectively). Of the 17 patients with the final diagnosis of the NSTEMI, 10 patients showed negative troponin T in the initial examination when they entered the Emergency Room. Of the 10 patients, 7 patients (70.0%) had positive hFABP in the initial examination at the moment they entered the Emergency Room. Such results indicated that examination of hFABP had sensitivity, negative predictive value, and higher accuracy compared to the troponin T in diagnosing the AMI onset of ≤6 hours. In the patients with the early onset of chest pain with ECG non-ST elevation and negative troponin T, the hFABP could be used to predict the incidence of AMI.

Copyright

© 2024 The Author(s)

Open Access

Open Access This chapter is licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license and indicate if changes were made.

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TY  - CONF
AU  - Jamaluddin Jamaluddin
AU  - Muzakkir Amir
AU  - Peter Kabo
AU  - Idar Mappangara
PY  - 2024
DA  - 2024/04/22
TI  - The Assessment of the Diagnostic Value of the Heart-Type Fatty Acid-Binding Protein (hFABP) in the Patients Suffering from Chest Pain and Suspected with Acute Coronary Syndrome
BT  - Proceedings of the 1st International Conference Medical and Health Science Halu Oleo (IMHO 2023)
PB  - Atlantis Press
SP  - 209
EP  - 219
SN  - 2468-5739
UR  - https://doi.org/10.2991/978-94-6463-392-4_24
DO  - 10.2991/978-94-6463-392-4_24
ID  - Jamaluddin2024
ER  -